Cytotoxin and helminthotoxin. MBP also induces non-cytolytic histamine release from basophils. It is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions.
Specificity
Natural and recombinant Rat Bone marrow proteoglycan
Subcellular Location
Cytoplasmic granule Matrix of eosinophil's large specific granule (crystalloid core).