JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Aprataxin

SKU : BHE13801236

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E9623r
Alternative Names	Forkhead-associated domain histidine triad-like protein ; FHA-HIT
Categories	Elisa
Function	DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.
Specificity	Natural and recombinant Rat Aprataxin
Subcellular Location	Nucleus nucleoplasm Nucleus nucleolus Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage. Colocalizes with MDC1 at sites of DNA double-strand breaks. Interaction with NCL is required for nucleolar localization.
Entryname	APTX_RAT
Protein Name	Aprataxin
Sequence	50: MRVCWLVRQD ; CWHQRIKLPH ; LEAVVIGRSP ; ETKITDKKCS ; RQQVQLKAEC ; 100: NKRYVNVKQM ; GVNPTSIDEV ; VIGKDREMKL ; LPGQVLHMVN ; ELYPYMVEFE ; 150: EVAESPNVTQ ; RKRKRPDCDS ; QEMEAEAGAS ; PSQCSVSPKT ; GKHGAAKEES ; 200: LGHWSQGLKI ; SMKDPKMQVY ; KDDQVVVIKD ; KYPKARHHWL ; VLPWASISSL ; 250: KVVTSEHLEL ; LKHMHAVGEK ; VIADFTGSSK ; LRFRLGYHAI ; PSMSHVHLHV ; 300: ISQDFDSPCL ; KNKKHWNSFN ; TEYFLESQAV ; IKMVQEAGRV ; TVKDGTCELL ; 329: KLPLRCHECQ ; QLLPSIPQLK ; EHLRKHWGG
Sequence Length	329
String	Q8K4H4
Sub Unit	Interacts with single-strand break repair proteins XRCC1, XRCC4, ADPRT and p53/TP53. Interacts with NCL. Interacts (via FHA-like domain) with MDC1 (phosphorylated).

Uniprot	Q8K4H4
Gene Name	Aptx
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:259271
Unigene	Rn.50459

Reference	1. "Identification of FHA-HIT as a novel nuclear protein involved in cell-cycle regulation." Huang C.-H., Chen H., Peng J., Chen Y. Submitted (2001-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Testis.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13801236	E9623r	96T	$796		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.