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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Alpha-ketoglutarate-dependent dioxygenase FTO

SKU : BHE13804142

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4267r
Alternative Names	Fat mass and obesity-associated protein
Categories	Elisa
Function	Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Specificity	Natural and recombinant Rat Alpha-ketoglutarate-dependent dioxygenase FTO
Subcellular Location	Nucleus
Detection Range	0.156-10ng/ml
Entryname	FTO_RAT
Method Type	Sandwich
Platform	PF12934
Protein Name	Alpha-ketoglutarate-dependent dioxygenase FTO
Sensitivity	0.086ng/mL
Sequence	50: MKRVQTAEER ; EREAKKLRLL ; EELEDTWLPY ; LTPKDDEFYQ ; QWQLKYPKLV ; 100: FREAGSIPEE ; LHKEVPEAFL ; TLHKHGCLFR ; DLVRIQGKDV ; LTPVSRILIG ; 150: DPGCTYKYLN ; TRLFTVPWPV ; KGCTINYTEA ; EIAAACQTFL ; KLNDYLQVET ; 200: IQALEELAIK ; EKANEDAVPL ; CMAEFPRAGV ; GPSCDDEVDL ; KSRAAYNVTL ; 250: LNFMDPQKMP ; YLKEEPYFGM ; GKMAVSWHHD ; ENLVDRSAVA ; VYSYSCEGSE ; 300: DESDDESSFE ; GRDPDTWHVG ; FKISWDIETP ; GLTIPLHQGD ; CYFMLDDLNA ; 350: THQHCVLAGS ; QPRFSSTHRV ; AECSTGTLDY ; ILQRCQLALQ ; NVLNDSDNGD ; 400: VSLKSFEPAV ; LKQGEEIHNE ; VEFEWLRQFW ; FQGNRYKICT ; DWWCEPMTQL ; 450: EGLWKKMESV ; TNAVLREVKR ; EGLSVEQRSE ; ILSAVLIPLT ; MRQNLRKEWH ; 500: ARCQARVVRT ; LPAQQKPDCR ; PYWEKDDPSM ; PLPFDLTDVV ; SEIRSQLLEA ; 502: RS
Sequence Length	502
String	Q2A121
Sub Unit	Monomer. may also exist as homodimer.

Uniprot	Q2A121
Gene Name	Fto
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:291905
Unigene	Rn.229320

Reference	1. "Expression of phosphoproteins and amelotin in teeth." Trueb B., Taeschler S., Schild C., Lang N.P. Int. J. Mol. Med.19:49-54(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY strain: Wistar. 2. "The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain." Fredriksson R., Hagglund M., Olszewski P.K., Stephansson O., Jacobsson J.A., Olszewska A.M., Levine A.S., Lindblom J., Schioth H.B. Endocrinology149:2062-2071(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY FASTING;TISSUE SPECIFICITY

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804142	E4267r	96T	$796		Add to Cart

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