ELISA Kit for Rat AKT-interacting protein

Mfr.No.	E14178r
Alternative Names	Fused toes protein homolog ; Fts
Categories	Elisa
Function	Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Specificity	Natural and recombinant Rat AKT-interacting protein
Subcellular Location	Cytoplasm Cell membrane Peripheral membrane protein
Detection Range	0.156-10ng/mL
Entryname	AKTIP_RAT
Method Type	Sandwich
Platform	PF00179
Protein Name	AKT-interacting protein
Sensitivity	0.068ng/mL
Sequence	50: MNPLWSMSSG ; SVRKRAEGEE ; KTLAGDVKTS ; PPRSAPKKQL ; PSIPKNALPI ; 100: SKPTSPAPAA ; QSTNGTHASY ; GPFYLEYSLL ; AEFTMVVKQK ; LPGVYVQPSY ; 150: RSALVWFGVI ; FIRHGLYQDG ; VFKFTVYIPD ; NYPDGDCPRL ; LFDIPVFHPL ; 200: VDPTSGELDV ; KRAFAKWRRN ; HNHIWQVLMY ; ARRVFYKIDT ; TSPLNPEAAV ; 250: LYEKDIQLFK ; SKVVDSVKVC ; TARLFDQPKI ; EDPYAISFSP ; WNPSVHDEAR ; 292: EKMLTQKKPD ; EQHNKSVHVA ; GLSWVKPGSV ; QPFSKEEKTV ; AT
Sequence Length	292
String	Q5FVH4
Sub Unit	Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with HOOK1, HOOK2 and HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex). Also interacts with AKT1.

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Brain.

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