Group VI phospholipase A2 ; GVI PLA2 ; Intracellular membrane-associated calcium-independent phospholipase A2 beta ; iPLA2-beta ; Patatin-like phospholipase domain-containing protein 9 ; PNPLA9 ; Pnpla9
Categories
Elisa
Function
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
Specificity
Natural and recombinant Rat 85/88 kDa calcium-independent phospholipase A2