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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig Tumor necrosis factor ligand superfamily member 6

SKU : BHE13811026

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0031p
Alternative Names	CD95 ligand ; CD95-L ; Fas antigen ligand ; Fas ligand ; CD178 ; CD95L ; FASL ; TNFSF6
Categories	Elisa
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Specificity	Natural and recombinant Pig Tumor necrosis factor ligand superfamily member 6
Subcellular Location	Tumor necrosis factor ligand superfamily member 6, soluble form Secreted May be released into the extracellular fluid, probably by cleavage form the cell surface.
Detection Range	78-5000pg/mL
Entryname	TNFL6_PIG
Method Type	Sandwich
Platform	PF00229
Protein Name	Tumor necrosis factor ligand superfamily member 6
Sensitivity	39pg/mL
Sequence	50: MQQPFNYPYP ; QIFWVDSSAT ; SPWASPGSVF ; PCPASVPGRP ; GQRRPPPPPP ; 100: PPPPPPTLLP ; SRPLPPLPPP ; SLKKKRDHNA ; GLCLLVMFFM ; VLVALVGLGL ; 150: GMFQLFHLQK ; ELTELRESAS ; QRHTESSLEK ; QIGHPNLPSE ; KKELRKVAHL ; 200: TGKPNSRSIP ; LEWEDTYGIA ; LVSGVKYMKG ; SLVINDTGLY ; FVYSKVYFRG ; 250: QYCNNQPLSH ; KVYTRNSRYP ; QDLVLMEGKM ; MNYCTTGQMW ; ARSSYLGAVF ; 282: NLTSADHLYV ; NVSELSLVNF ; EESKTFFGLY ; KL
Sequence Length	282
Sub Unit	Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.

Uniprot	Q9BEA8
Gene Name	FASLG
Immunogen Species	Sus Scrofa (Pig)
Kegg	ssc:396726
Unigene	Ssc.15870

Reference	1. "Molecular cloning, characterization, and expression of porcine Fas ligand (CD95 ligand)." Muneta Y., Shimoji Y., Inumaru S., Mori Y. J. Interferon Cytokine Res.21:305-312(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Porcine Fas-ligand gene: genomic sequence analysis and comparison with human gene." Motegi-Ishiyama Y., Nakajima Y., Hoka S., Takagaki Y. Mol. Immunol.38:581-586(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] strain: Landrace X Large Yorkshire white. tissue: Thymocyte. 3. "Cloning and potential utility of porcine Fas ligand: overexpression in porcine endothelial cells protects them from attack by human cytolytic cells." Tsuyuki S., Kono M., Bloom E.T. Xenotransplantation9:410-421(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Lymphoid tissue. 4. "Molecular cloning and characterization of porcine Fas ligand cDNA." Zhu N., Young Y. Submitted (2001-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Guanxi bama miniature pig.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811026	E0031p	96T	$900		Add to Cart

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