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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig Transcription factor AP-1

SKU : BHE13805791

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1292p
Alternative Names	Activator protein 1 ; AP1 ; Proto-oncogene c-Jun ; V-jun avian sarcoma virus 17 oncogene homolog
Categories	Elisa
Function	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Specificity	Natural and recombinant Pig Transcription factor AP-1
Subcellular Location	Nucleus
Entryname	JUN_PIG
Platform	PF00170
Protein Name	Transcription factor AP-1
Sequence	50: MTAKMETTFY ; DDALNASFLQ ; SESGAYGYSN ; PKILKQSMTL ; NLADPVGNLK ; 100: PHLRAQDSDL ; LTSPDVGLLK ; LASPELERLI ; IQSSNGHITT ; TPTPTQFLCP ; 150: KNVTDEQEGF ; AEGFVRALAE ; LHSQNTLPSV ; TSAAQPVSGA ; GLVAPAVASV ; 200: AGGSGSGGFS ; ASLHSEPPVY ; ANLSNFNPGA ; LSSGGGAPSY ; GAAGLAFPAQ ; 250: PQQQQQQPPQ ; PPHHLPVQHP ; RLQALKEEPQ ; TVPEMPGETP ; PLSPIDMESQ ; 300: ERIKAERKRM ; RNRIAASKCR ; KRKLERIARL ; EEKVKTLKAQ ; NSELASTANM ; 331: LREQVAQLKQ ; KVMNHVNSGC ; QLMLTQQLQT ; F
Sequence Length	331
String	P56432
Sub Unit	Heterodimer with either FOS or BATF3 or ATF7 (By similarity). The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex (By similarity). Interacts with RNF187 and HIPK3.

Uniprot	P56432
Gene Name	JUN
Immunogen Species	Sus Scrofa (Pig)
Kegg	ssc:396913
Unigene	Ssc.97579

Reference	1. "Molecular cloning of c-jun and c-fos cDNAs from porcine anterior pituitary and their involvement in gonadotropin-releasing hormone stimulation." Chung H.-O., Kato T., Kato Y. Mol. Cell. Endocrinol.119:75-82(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Pituitary anterior lobe. 2. Chung H.-O., Kato T., Kato Y. Mol. Cell. Endocrinol.122:113-114(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805791	E1292p	96T	$900		Add to Cart

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