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ELISA Kit for Pig Thioredoxin-interacting protein

SKU : BHE13811536

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1162p
Categories	Elisa
Function	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
Specificity	Natural and recombinant Pig Thioredoxin-interacting protein
Subcellular Location	Cytoplasm
Entryname	TXNIP_PIG
Platform	PF02752
Protein Name	Thioredoxin-interacting protein
Sequence	50: MVMFKKIKSF ; EVVFNDPEKV ; YGCGEKVAGR ; VIVEVCEVTR ; IKAVRILACG ; 100: VAKVLWMQGS ; QQCKQTLDYL ; RYEDTLLLDD ; HPTGENEMVI ; MRPGNKYEYK ; 150: FGFELPQGPL ; GTSFKGKYGC ; VDYWVKAFLD ; RPSQPTQETK ; KHFEVMDLVD ; 200: VNTPDLMAPV ; SAKKEKKVSC ; MFIPDGRVSV ; SARIDRKGFC ; EGDEINIHAD ; 250: FENTCSRIVV ; PKAAIVARHT ; YLANGQTKVL ; TQKLSSVRGN ; HIISGTCASW ; 300: RGKSLRVQKI ; RPSILGCNIL ; RVEYFLLIYV ; SVPGSKKVIL ; DLPLVIGSRS ; 350: GLSSRTSSMA ; SRTSSEMSWV ; DLNIPDTPEA ; PPCYMDIIPE ; DHRLESPTTP ; 391: LLDDTDGSQD ; SPIFMYAPEF ; KFMPPPTYSE ; VDPCILNNNV ; Q
Sequence Length	391
Sub Unit	Interacts with TXN/thioredoxin through its redox-active site. Interacts with transcriptional repressors ZBTB16, ZBTB32 and HDAC1 (By similarity). Interacts (via C-terminus) with ITCH (via WW domains).

Uniprot	Q2HY40
Gene Name	TXNIP
Immunogen Species	Sus Scrofa (Pig)
Kegg	ssc:733688
Unigene	Ssc.16648

Reference	1. "Investigation of TXNIP (thioredoxin-interacting protein) and TRX (thioredoxin) genes for growth-related traits in pigs." Yu M., Geiger B., Deeb N., Rothschild M.F. Mamm. Genome18:197-209(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. "Polymorphism and association with production traits of porcine TXNIP gene." Xu D.Q., Ling X.F., Xiong Y.Z. Submitted (2005-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 3. "Molecular cloning and characterization of porcine TXNIP." Xu D.Q., Xiong Y.Z. Submitted (2006-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Skeletal muscle.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811536	E1162p	96T	$900		Add to Cart

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