In presence of calcium ions, PSAP binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Specificity
Natural and recombinant Pig Pulmonary surfactant-associated protein A
Subcellular Location
Secreted extracellular space extracellular matrix Secreted extracellular space surface film
"A cDNA clone for the porcine pulmonary surfactant - associated protein (PSP-A)." Adamou J.E., Elshourbagy N.A. Submitted (1995-04) to the EMBL/GenBank/DDBJ databases
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