May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity). Interacts with FKBP4.
Specificity
Natural and recombinant Pig Protein S100-A6
Subcellular Location
Nucleus envelope Cytoplasm Cell membrane Peripheral membrane protein Cytoplasmic side
Homodimer; head to tail assembly of 2 subunits. Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1 and CACYBP. Interacts with TP53. Interacts with tropomyosin.