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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig Presenilin-2

SKU : BHE13809415

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1274p
Categories	Elisa
Function	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Specificity	Natural and recombinant Pig Presenilin-2
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein
Entryname	PSN2_PIG
Platform	PF01080
Protein Name	Presenilin-2
Sequence	50: MLTFMASDSE ; EEVCDERTSL ; MSAESPTPRS ; CQEGRQGLED ; GESAAQWRSQ ; 100: DSEEDHEEDP ; DRYVCSGVPG ; RPPGLEEELT ; LKYGAKHVIM ; LFVPVTLCMI ; 150: VVVATIKSVR ; FYTEKNGQLI ; YTPFTEDTPS ; VGQRLLNSVL ; NTLIMISVIV ; 200: VMTIFLVVLY ; KYRCYKFIHG ; WLITSSLMLL ; FLFTYIYLGE ; VLKTYNVAMD ; 250: YPTLFLTVWN ; FGAVGMVCIH ; WKGPLVLQQA ; YLIMISALMA ; LVFIKYLPEW ; 300: SAWVILGAIS ; VYDLVAVLCP ; KGPLRMLVET ; AQERNEPIFP ; ALIYSSAMVW ; 350: TVGMAKLDPS ; SQGALQLPYD ; PEMEEDSYDS ; FGEPSYPEVF ; EPPLPGYPGE ; 400: ELEEEEERGV ; KLGLGDFIFY ; SVLVGKAAAT ; GSGDWNTTLA ; CFVAILIGLC ; 448: LTLLLLAVFK ; KALPALPISI ; TFGLIFYFST ; DNLVRPFMDT ; LASHQLYI
Sequence Length	448
String	Q0MS45
Sub Unit	Homodimer. Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist. Interacts with DOCK3. Interacts with HERPUD1, FLNA, FLNB and PARL.

Uniprot	Q0MS45
Gene Name	PSEN2
Immunogen Species	Sus Scrofa (Pig)
Kegg	ssc:780410
Unigene	Ssc.54979

Reference	1. "Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain." Madsen L.B., Thomsen B., Larsen K., Bendixen C., Holm I.E., Fredholm M., Joergensen A.L., Nielsen A.L. BMC Neurosci.8:72-72(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY tissue: Brain. tissue: Liver. tissue: Lymphocyte. 2. Wang G. Submitted (2007-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809415	E1274p	96T	$900		Add to Cart

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