Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Specificity
Natural and recombinant Pig Platelet-derived growth factor subunit B
Subcellular Location
Secreted
Detection Range
78-5000pg/mL
Entryname
PDGFB_PIG
Method Type
Sandwich
Protein Name
Platelet-derived growth factor subunit B
Sensitivity
35pg/mL
Sequence
15:
SLGSPAVAEP ; AVIAE
Sequence Length
15
Sub Unit
Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with XLKD1.