Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
Specificity
Natural and recombinant Pig Orexin
Subcellular Location
Rough endoplasmic reticulum Cytoplasmic vesicle Cell junction synapse Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SYNTHESIS OF OREXIN-B