UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
Specificity
Natural and recombinant Pig Mitochondrial uncoupling protein 3
Subcellular Location
Mitochondrion inner membrane Multi-pass membrane protein
"Characterization of the porcine uncoupling proteins 2 and 3 (UCP2 and 3) and their localization to chromosome 9p by somatic cell hybrids." Werner P., Nowaczyk K., Neuenschwander S., Strazinger G. Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
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"First evidence of uncoupling protein (UCP) gene expression in piglet skeletal muscle." Damon M., Vincent A., Herpin P. Submitted (1999-02) to the EMBL/GenBank/DDBJ databases
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