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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig Insulin-like growth factor 1 receptor

SKU : BHE13805661

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1200p
Alternative Names	Insulin-like growth factor I receptor ; IGF-I receptor ; CD221
Categories	Elisa
Function	This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Specificity	Natural and recombinant Pig Insulin-like growth factor 1 receptor
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	IGF1R_PIG
Method Type	Sandwich
Platform	PF00041
Protein Name	Insulin-like growth factor 1 receptor
Sensitivity	27pg/mL
Sequence	50: ERTVISNLRP ; FTLYRIDIHS ; CNHEAEKLGC ; SASNFVFART ; MPAEGADDIP ; 100: GPVTWEPRPE ; NSIFLKWPEP ; ENPNGLILMY ; EIKYGSQVED ; QRECVSRQEY ; 150: RKYGGAKLNR ; LNPGNYTARI ; QATSLSGNGS ; WTEPVFFYVQ ; AKTTYENFIH ; 200: LIIALPVAVL ; LIVGGLVIML ; YVFHRKRNNS ; RLGNGVMLFE ; LMRMCWQYNP ; 250: KMRPSFLEII ; SSIKDEMEPG ; FREVSFYYSE ; ENKPPEPEEL ; DLEPENMESV ; 300: PLDPSASSSS ; LPLPDRHSGH ; KAENGPGPGV ; LVLRASFDER ; QPYAHMNGGR ; 304: KNER
Sequence Length	304
String	Q29000
Sub Unit	Tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chain carries the kinase domain. Forms a hybrid receptor with INSR, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with GNB2L1/RACK1.

Uniprot	Q29000
Gene Name	IGF1R
Immunogen Species	Sus Scrofa (Pig)
Unigene	Ssc.54172

Reference	1. Matteri R.L., Anderson J.E., Prather R.S. Submitted (1996-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-186 tissue: Skeletal muscle. 2. "Developmental regulation of steroidogenic enzyme gene expression in the periimplantation porcine conceptus: a paracrine role for insulin-like growth factor-I." Green M.L., Simmen R.C.M., Simmen F.A. Endocrinology136:3961-3970(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 187-304 tissue: Conceptus membrane.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805661	E1200p	96T	$900		Add to Cart

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