ELISA Kit for Pig Bcl-2-like protein 1

Mfr.No.	E15265p
Alternative Names	Apoptosis regulator Bcl-X ; BCLX ; BLC2L
Categories	Elisa
Function	Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1.Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane.
Specificity	Natural and recombinant Pig Bcl-2-like protein 1
Subcellular Location	Mitochondrion membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Cytoplasmic side Mitochondrial membranes and perinuclear envelope.
Entryname	B2CL1_PIG
Platform	PF00452
Protein Name	Bcl-2-like protein 1
Sequence	50: MSQSNRELVV ; DFLSYKLSQK ; GYSWSQFTDV ; EENRTEAPEG ; TESEAETPSA ; 100: INGNPSWHLA ; DSPAVNGATG ; HSSSLDAREV ; IPMAAVKQAL ; REAGDEFELR ; 150: YRRAFSDLTS ; QLHITPGTAY ; QSFEQVLNEL ; FRDGVNWGRI ; VAFFSFGGAL ; 200: CVESVDKEMQ ; VLVSRIATWM ; ATYLNDHLEP ; WIQENGGWDT ; FVELYGNNAA ; 233: AESRKGQERF ; NRWFLTGMTL ; AGVVLLGSLF ; SRK
Sequence Length	233
String	O77737
Sub Unit	Bcl-X(L) forms heterodimers with BAX, BAK and BCL2 (By similarity). Heterodimerization with BAX does not seem to be required for anti-apoptotic activity (By similarity). Also interacts with BBC3 (By similarity). Isoform Bcl-X(L) binds to Siva isoform 1. Interacts with BECN1, BCL2L11 and PGAM5 (By similarity). Isoform Bcl-X(L) interacts with IKZF3.

Reference	1. "Quantification of cardioprotective gene expression in porcine short-term hibernating myocardium." Bartling B., Hoffmann J., Holtz J., Schulz R., Heusch G., Darmer D. J. Mol. Cell. Cardiol.31:147-158(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801709	E15265p	96T	$900		Add to Cart