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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig 5'-AMP-activated protein kinase subunit beta-1

SKU : BHE13800329

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1671p
Alternative Names	5'-AMP-activated protein kinase 40 kDa subunit
Categories	Elisa
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Specificity	Natural and recombinant Pig 5'-AMP-activated protein kinase subunit beta-1
Entryname	AAKB1_PIG
Method Type	Sandwich
Protein Name	5'-AMP-activated protein kinase subunit beta-1
Sequence	50: ILMDSPEDAD ; LYHSEEIKAP ; EKEEFLAWQH ; DLEVNDKASA ; QARPTVFRWT ; 100: GGGKEVYLSG ; SFNNWSKLPL ; TRSHNNFVAI ; LDLPEGEHQY ; KFLVDGQWTH ; 122: DPSEPVVTSQ ; LGTVNNIIQV ; KK
Sequence Length	122
String	P80387
Sub Unit	AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.

Uniprot	P80387
Gene Name	PRKAB1
Immunogen Species	Sus Scrofa (Pig)

Reference	1. "Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase." Stapleton D., Gao G., Michell B.J., Widmer J., Mitchelhill K.I., Teh T., House C.M., Witters L.A., Kemp B.E. J. Biol. Chem.269:29343-29346(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 15-120;PROTEIN SEQUENCE OF 1-21; 23-86 AND 92-122 tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800329	E1671p	96T	$900		Add to Cart

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