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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse X-box-binding protein 1

SKU : BHE13811215

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9143m
Alternative Names	Tax-responsive element-binding protein 5 ; TREB-5 ; Treb5
Categories	Elisa
Function	Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE) (By similarity). Isoform 2 is involved in controlling the production of interleukin-6.
Specificity	Natural and recombinant Mouse X-box-binding protein 1
Subcellular Location	Nucleus
Detection Range	0.78-50ng/mL
Entryname	XBP1_MOUSE
Method Type	Sandwich
Platform	PF07716
Protein Name	X-box-binding protein 1
Sensitivity	0.3ng/mL
Sequence	50: MVVVAAAPSA ; ATAAPKVLLL ; SGQPASGGRA ; LPLMVPGPRA ; AGSEASGTPQ ; 100: ARKRQRLTHL ; SPEEKALRRK ; LKNRVAAQTA ; RDRKKARMSE ; LEQQVVDLEE ; 150: ENHKLQLENQ ; LLREKTHGLV ; VENQELRTRL ; GMDTLDPDEV ; PEVEAKGSGV ; 200: RLVAGSAESA ; ALRLCAPLQQ ; VQAQLSPPQN ; IFPWTLTLLP ; LQILSLISFW ; 250: AFWTSWTLSC ; FSNVLPQSLL ; VWRNSQRSTQ ; KDLVPYQPPF ; LCQWGPHQPS ; 267: WKPLMNSFVL ; TMYTPSL
Sequence Length	267
String	O35426

Uniprot	O35426
Gene Name	Xbp1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:22433
Unigene	Mm.469937

Reference	1. "Isolation and characterization of the gene encoding mouse tax-responsive element-binding protein (TREB) 5." Masaki T., Noguchi H., Kobayashi M., Yoshida M., Takamatsu K. DNA Res.7:187-193(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA." Calfon M., Zeng H., Urano F., Till J.H., Hubbard S.R., Harding H.P., Clark S.G., Ron D. Nature415:92-96(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);INDUCTION strain: 129/SvEv. 3. "Sequence analysis of murine XBP-1." Lee C.M., Reddy E.P. Submitted (2001-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) 4. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) strain: FVB/N. tissue: Mammary tumor. 6. "XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response." Lee A.H., Iwakoshi N.N., Glimcher L.H. Mol. Cell. Biol.23:7448-7459(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION 7. "Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1." Iwakoshi N.N., Lee A.-H., Vallabhajosyula P., Otipoby K.L., Rajewsky K., Glimcher L.H. Nat. Immunol.4:321-329(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION

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BHE13811215	E9143m	96T	$776		Add to Cart

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