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ELISA Kit for Mouse Vasodilator-stimulated phosphoprotein

SKU : BHE13810707

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9578m
Categories	Elisa
Function	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
Specificity	Natural and recombinant Mouse Vasodilator-stimulated phosphoprotein
Subcellular Location	Cytoplasm Cytoplasm cytoskeleton Cell junction focal adhesion Cell projection lamellipodium membrane Cell projection filopodium membrane Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions.
Entryname	VASP_MOUSE
Method Type	Sandwich
Platform	PF11643
Protein Name	Vasodilator-stimulated phosphoprotein
Sequence	50: MSETVICSSR ; ATVMLYDDSN ; KRWLPAGTGP ; QAFSRVQIYH ; NPTANSFRVV ; 100: GRKMQPDQQV ; VINCAIIRGV ; KYNQATPIFH ; QWRDARQVWG ; LNFGSKEDAI ; 150: QFATGMANAL ; EALEGGGPPP ; APAPPAWSAQ ; NGPSPEELEQ ; QKRQPEHMER ; 200: RVSNAGGPPA ; PPAGGPPPPP ; GPPPPPGPPP ; PPGLPSSGVS ; GAGHGAGAAP ; 250: PPAPPLPTAQ ; GPNSGGSGAP ; GLAAAIAGAK ; LRKVSKQEEA ; SGGPLAPKAE ; 300: NSRSTGGGLM ; EEMNAMLARR ; RKATQVGEKP ; PKDESASEES ; EARLPAQSEP ; 350: VRRPWEKNST ; TLPRMKSSSS ; VTTSEAHPST ; PCSSDDSDLE ; RVKQELLEEV ; 375: RKELQKMKEE ; IIEVFVQELR ; KRGSP
Sequence Length	375
String	P70460
Sub Unit	Homotetramer (By similarity). Interacts with PFN1, PFN2, LPP, ACTN1 and ACTG1. Interacts, via the EVH1 domain, with the Pro-rich regions of ZYX. This interaction is important for targeting to focal adhesions and the formation of actin-rich structures at the apical surface of cells. Interacts, via the EVH1 domain, with the Pro-rich domain of Listeria monocytogenes actA. Interacts with APBB1IP. Interacts, via the Pro-rich domain, with the C-terminal SH3 domain of DNMBP.

Uniprot	P70460
Gene Name	Vasp
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:22323
Unigene	Mm.9684

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810707	E9578m	96T	$776		Add to Cart

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