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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse V-type proton ATPase 116 kDa subunit a isoform 2

SKU : BHE13811661

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4689m
Alternative Names	Immune suppressor factor J6B7 ; ISF ; Lysosomal H(+)-transporting ATPase V0 subunit a2 ; ShIF ; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 ; Atp6n1b ; Tj6
Categories	Elisa
Function	Part of the proton channel of V-ATPases (By similarity). Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH.
Specificity	Natural and recombinant Mouse V-type proton ATPase 116 kDa subunit a isoform 2
Subcellular Location	Cell membrane Multi-pass membrane protein Endosome membrane In kidney proximal tubules, detected in subapical early endosomes.
Detection Range	0.312-20ng/mL
Entryname	VPP2_MOUSE
Method Type	Sandwich
Platform	PF01496
Protein Name	V-type proton ATPase 116 kDa subunit a isoform 2
Sensitivity	0.085ng/mL
Sequence	50: MGSLFRSESM ; CLAQLFLQSG ; TAYECLSALG ; EKGLVQFRDL ; NQNVSSFQRK ; 100: FVGEVKRCEE ; LERILVYLVQ ; EITRADIPLP ; EGEASPPAPP ; LKHVLEMQEQ ; 150: LQKLEVELRE ; VTKNKEKLRK ; NLLELVEYTH ; MLRVTKTFLK ; RNVEFEPTYE ; 200: EFPALENDSL ; LDYSCMQRLG ; AKLGFVSGLI ; QQGRVEAFER ; MLWRACKGYT ; 250: IVTYAELDEC ; LEDPETGEVI ; KWYVFLISFW ; GEQIGHKVKK ; ICDCYHCHIY ; 300: PYPNTAEERR ; EIQEGLNTRI ; QDLYTVLHKT ; EDYLRQVLCK ; AAESVCSRVV ; 350: QVRKMKAIYH ; MLNMCSFDVT ; NKCLIAEVWC ; PEVDLPGLRR ; ALEEGSRESG ; 400: ATIPSFMNTI ; PTKETPPTLI ; RTNKFTEGFQ ; NIVDAYGVGS ; YREVNPALFT ; 450: IITFPFLFAV ; MFGDFGHGFV ; MFLFALLLVL ; NENHPRLSQS ; QEILRMFFDG ; 500: RYILLLMGLF ; SVYTGLIYND ; CFSKSVNLFG ; SGWNVSAMYS ; SSHSPEEQRK ; 550: MVLWNDSTIR ; HSRTLQLDPN ; IPGVFRGPYP ; FGIDPIWNLA ; TNRLTFLNSF ; 600: KMKMSVILGI ; FHMTFGVVLG ; IFNHLHFRKK ; FNVYLVSVPE ; ILFMLCIFGY ; 650: LIFMIIYKWL ; AYSAETSREA ; PSILIEFINM ; FLFPTSKTHG ; LYPGQAHVQR ; 700: VLVALTVLAV ; PVLFLGKPLF ; LLWLHNGRNC ; FGMSRSGYTL ; VRKDSEEEVS ; 750: LLGNQDIEEG ; NSRMEEGCRE ; VTCEEFNFGE ; ILMTQAIHSI ; EYCLGCISNT ; 800: ASYLRLWALS ; LAHAQLSDVL ; WAMLMRVGLR ; VDTTYGVLLL ; LPVMAFFAVL ; 850: TIFILLVMEG ; LSAFLHAIRL ; HWVEFQNKFY ; VGAGTKFVPF ; SFSLLSSKFS ; 856: NDDSIA
Sequence Length	856
String	P15920
Sub Unit	The V-ATPase is an heteromultimeric enzyme composed of at least thirteen different subunits. It has a membrane peripheral V1 sector for ATP hydrolysis and an integral V0 for proton translocation. The V1 sector comprises subunits A-H, whereas V0 includes subunits a, d, c, c', and c''. Directly interacts with PSCD2 through its N-terminal cytosolic tail in an intra-endosomal acidification-dependent manner. Disruption of this interaction results in the inhibition of endocytosis.

Uniprot	P15920
Gene Name	Atp6v0a2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21871
Unigene	Mm.1158

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811661	E4689m	96T	$776		Add to Cart

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