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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Ubiquitin-conjugating enzyme E2 B

SKU : BHE13810800

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1063m
Alternative Names	E2 ubiquitin-conjugating enzyme B ; E214K ; RAD6 homolog B ; HR6B ; Ubiquitin carrier protein B ; Ubiquitin-protein ligase B ; Rad6b
Categories	Elisa
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.
Specificity	Natural and recombinant Mouse Ubiquitin-conjugating enzyme E2 B
Subcellular Location	Cell membrane Nucleus In peripheral neurons, expressed both at the plasma membrane and in nuclei.
Detection Range	0.312-20ng/mL
Entryname	UBE2B_MOUSE
Method Type	Sandwich
Platform	PF00179
Protein Name	Ubiquitin-conjugating enzyme E2 B
Sensitivity	0.1ng/mL
Sequence	50: MSTPARRRLM ; RDFKRLQEDP ; PVGVSGAPSE ; NNIMQWNAVI ; FGPEGTPFED ; 100: GTFKLVIEFS ; EEYPNKPPTV ; RFLSKMFHPN ; VYADGSICLD ; ILQNRWSPTY ; 150: DVSSILTSIQ ; SLLDEPNPNS ; PANSQAAQLY ; QENKREYEKR ; VSAIVEQSWN ; 152: DS
Sequence Length	152
String	P63147
Sub Unit	Interacts with RAD18, UBR2 and WAC.

Uniprot	P63147
Gene Name	Ube2b
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:22210
Unigene	Mm.384918

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810800	E1063m	96T	$776		Add to Cart

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