ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 10B

Mfr.No.	E8953m
Alternative Names	Death receptor 5 ; MK ; CD262 ; Dr5 ; Killer
Categories	Elisa
Function	Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Specificity	Natural and recombinant Mouse Tumor necrosis factor receptor superfamily member 10B
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.78-50ng/mL
Entryname	TR10B_MOUSE
Method Type	Sandwich
Platform	PF00531
Protein Name	Tumor necrosis factor receptor superfamily member 10B
Sensitivity	0.405ng/mL
Sequence	50: MEPPGPSTPT ; ASAAARADHY ; TPGLRPLPKR ; RLLYSFALLL ; AVLQAVFVPV ; 100: TANPAHNRPA ; GLQRPEESPS ; RGPCLAGQYL ; SEGNCKPCRE ; GIDYTSHSNH ; 150: SLDSCILCTV ; CKEDKVVETR ; CNITTNTVCR ; CKPGTFEDKD ; SPEICQSCSN ; 200: CTDGEEELTS ; CTPRENRKCV ; SKTAWASWHK ; LGLWIGLLVP ; VVLLIGALLV ; 250: WKTGAWRQWL ; LCIKRGCERD ; PESANSVHSS ; LLDRQTSSTT ; NDSNHNTEPG ; 300: KTQKTGKKLL ; VPVNGNDSAD ; DLKFIFEYCS ; DIVPFDSWNR ; LMRQLGLTDN ; 350: QIQMVKAETL ; VTREALYQML ; LKWRHQTGRS ; ASINHLLDAL ; EAVEERDAME ; 381: KIEDYAVKSG ; RFTYQNAAAQ ; PETGPGGSQC ; V
Sequence Length	381
String	Q9QZM4
Sub Unit	Homotrimer. Can interact with TRADD and RIPK1.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810835	E8953m	96T	$776		Add to Cart