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ELISA Kit for Mouse Transcription initiation factor TFIID subunit 1

SKU : BHE13810463

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E8802m
Alternative Names	Cell cycle gene 1 protein ; TBP-associated factor 250 kDa ; p250 ; Transcription initiation factor TFIID 250 kDa subunit ; TAF(II)250 ; Ccg1
Categories	Elisa
Function	Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.
Specificity	Natural and recombinant Mouse Transcription initiation factor TFIID subunit 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	TAF1_MOUSE
Method Type	Sandwich
Platform	PF00439
Protein Name	Transcription initiation factor TFIID subunit 1
Sensitivity	0.177ng/mL
Sequence	50: MGPGWAGLLQ ; DKGGGSPSVV ; MSDTDSDEES ; AGGGPFSLTG ; FLFGNINGAG ; 100: QLEGESVLDD ; ECKKHLAGLG ; ALGLGSLITE ; LTANEELSGS ; DGALVNDEGW ; 150: IRSREDAVDY ; SDINEVAEDE ; SRRYQQTMGS ; LQPLCHTDYD ; EDDYDADCED ; 200: IDCKLMPPPP ; PPPGPLKKEK ; DQDDITGVSE ; DGEGIILPSI ; IAPSSLASEK ; 250: VDFSSSSDSE ; SEMGPQDAAQ ; SESKDGQLTL ; PLAGIMQHDA ; TKLLPSVTEL ; 300: FPEFRPGKVL ; RFLRLFGPGK ; NVPSVWRSAR ; RKRKKKHREL ; IQEGQVQEEE ; 350: CSVELEVNQK ; SLWNYDYAPP ; PLPDQCLSDD ; EITMMAPVES ; KFSQSTGDTD ; 400: KVMDTKPRVA ; EWRYGPARLW ; YDMLGVPEDG ; SGFDYGFKMK ; KTEHESTIKC ; 450: NIMKKLRKLE ; ENSGVDLLAD ; ENFLMVTQLH ; WEDDIIWDGE ; DVKHKGTKPQ ; 500: RASLAGWLPS ; SMTRNAMAYN ; VQQGFTATLD ; DDKPWYSIFP ; IDNEDLVYGR ; 550: WEDNIIWDAQ ; NMPRILEPPV ; LTLDPNDENL ; ILEIPDEKEE ; ATSNSPSKEN ; 600: KKESSLKKSR ; ILLGKTGVIK ; EEPQQNMSQP ; EVKDPWNLSN ; DEYYYPKQQG ; 650: LRGTFGGNII ; QHSIPAVELR ; QPFFPTHMGP ; IKLRQFHRPP ; LKKYSFGALS ; 700: QPGPHSVQPL ; LKHIKKKAKM ; REQERQASGG ; GEMFFMRTPQ ; DLTGKDGDLI ; 750: LAEYSEENGP ; LMMQVGMATK ; IKNYYKRKPG ; KDPGAPDCKY ; GETVYCHTSP ; 800: FLGSLHPGQL ; LQAFENNLFR ; APIYLHKMPE ; SDFLIIRTRQ ; GYFIRELVDI ; 850: FVVGQQCPLF ; EVPGPNSKRA ; NTHIRDFLQV ; FIYRLFWKSK ; DRPRRIRMED ; 900: IKKAFPSHSE ; SSIRKRLKLC ; ADFKRTGMDS ; NWWVLKSDFR ; LPTEEEIRAM ; 950: VSPEQCCAYY ; SMIAAEQRLK ; DAGYGEKSFF ; APEEENEEDF ; QMKIDDEVRT ; 1000: APWNTTRAFI ; AAMKGKCLLE ; VTGVADPTGC ; GEGFSYVKIP ; NKPTQQKDDK ; 1050: EPQPVKKTVT ; GTDADLRRLS ; LKNAKQLLRK ; FGVPEEEIKK ; LSRWEVIDVV ; 1100: RTMSTEQARS ; GEGPMSKFAR ; GSRFSVAEHQ ; ERYKEECQRI ; FDLQNKVLSS ; 1150: TEVLSTDTDS ; SSAEDSDFEE ; MGKNIENMLQ ; NKKTSSQLSR ; EREEQERKEL ; 1200: QRMLLAAGSA ; AAGNNHRDDD ; TASVTSLNSS ; ATGRCLKIYR ; TFRDEEGKEY ; 1250: VRCETVRKAT ; VIDAYVRIRT ; TKDEEFIRKF ; ALFDEQHREE ; MRKERRRIQE ; 1300: QLRRLKRNQE ; KEKLKGPPEK ; KPKKMKERPD ; LKLKCGACGA ; IGHMRTNKFC ; 1350: PLYYQTNAPP ; SNPVAMTEEQ ; EEELEKTVIH ; NDNEELIKVE ; GTKIVLGKQL ; 1400: IESADEVRRK ; SLVLKFPKQQ ; LPPKKKRRVG ; TTVHCDYLNR ; PHKSIHRRRT ; 1450: DPMVTLSSIL ; ESIINDMRDL ; PNTYPFHTPV ; NAKVVKDYYK ; IITRPMDLQT ; 1500: LRENVRKRLY ; PSREEFREHL ; ELIVKNSATY ; NGPKHSLTQI ; SQSMLDLCDE ; 1550: KLKEKEDKLA ; RLEKAINPLL ; DDDDQVAFSF ; ILDNIVTQKM ; MAVPDSWPFH ; 1600: HPVNKKFVPD ; YYKVIVSPMD ; LETIRKNISK ; HKYQSRESFL ; DDVNLILANS ; 1650: VKYNGPESQY ; TKTAQEIVNV ; CHQTLTEYDE ; HLTQLEKDIC ; TAKEAALEEA ; 1700: ELESLDPMTP ; GPYTPQPPDL ; YDNNTSLSVS ; RDASVYQDES ; NLSVLDIPSA ; 1750: TSEKQLTQEG ; GDGDGDLADE ; EEGTVQQPQA ; SVLYEDLLMS ; EGEDDEEDAG ; 1800: SDEEGDNPFF ; AIQLSESGSD ; SDVESGSLRP ; KQPRVLQENT ; RMGMENEESM ; 1850: MSYEGDGGDA ; SRGLEDSNIS ; YGSYEEPDPK ; SNTQDTSFSS ; IGGYEVSEEE ; 1891: EDEEEQRSGP ; SVLSQVHLSE ; DEEDSEDFHS ; IAGDTDLDSD ; E
Sequence Length	1891
String	Q80UV9
Sub Unit	TAF1 is the largest component of transcription factor TFIID that is composed of TBP and a variety of TBP-associated factors. TAF1, when part of the TFIID complex, interacts with C-terminus of TP53. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. RB1 interacts with the N-terminal domain of TAF1. Interacts with ASF1A and ASF1B.

Uniprot	Q80UV9
Gene Name	Taf1
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.261750

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BHE13810463	E8802m	96T	$776		Add to Cart

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