JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Transcription factor Sp1

SKU : BHE13809926

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E15093m
Categories	Elisa
Function	Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter Plays an essential role in the regulation of FE65 gene expression.
Specificity	Natural and recombinant Mouse Transcription factor Sp1
Subcellular Location	Nucleus Cytoplasm Nuclear location is goveed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
Detection Range	78-5000pg/mL
Entryname	SP1_MOUSE
Method Type	Sandwich
Platform	PF00096
Protein Name	Transcription factor Sp1
Sensitivity	39.3pg/mL
Sequence	50: MSDQDHSMDE ; VTAVVKIEKD ; VGGNNGGSGN ; GGGAAFSQTR ; SSSTGSSSSS ; 100: GGGGGQESQP ; SPLALLAATC ; SRIESPNENS ; NNSQGPSQSG ; GTGELDLTAT ; 150: QLSQGANGWQ ; IISSSSGATP ; TSKEQSGNST ; NGSNGSESSK ; NRTVSGGQYV ; 200: VAATPNLQNQ ; QVLTGLPGVM ; PNIQYQVIPQ ; FQTVDGQQLQ ; FAATGAQVQQ ; 250: DGSGQIQIIP ; GANQQIIPNR ; GSGGNIIAAM ; PNLLQQAVPL ; QGLANNVLSG ; 300: QTQYVTNVPV ; ALNGNITLLP ; VNSVSAATLT ; PSSQAGTISS ; SGSQESSSQP ; 350: VTSGTAISSA ; SLVSSQASSS ; SFFTNANSYS ; TTTTTSNMGI ; MNFTSSGSSG ; 400: TSSQGQTPQR ; VGGLQGSDSL ; NIQQNQTSGG ; SLQGSQQKEG ; EQSQQTQQQQ ; 450: ILIQPQLVQG ; GQALQALQAA ; PLSGQTFTTQ ; AISQETLQNL ; QLQAVQNSGP ; 500: IIIRTPTVGP ; NGQVSWQTLQ ; LQNLQVQNPQ ; AQTITLAPMQ ; GVSLGQTSSS ; 550: NTTLTPIASA ; ASIPAGTVTV ; NAAQLSSMPG ; LQTINLSALG ; TSGIQVHQLP ; 600: GLPLAIANTP ; GDHGTQLGLH ; GSGGDGIHDE ; TAGGEGENSS ; DLQPQAGRRT ; 650: RREACTCPYC ; KDSEGRASGD ; PGKKKQHICH ; IQGCGKVYGK ; TSHLRAHLRW ; 700: HTGERPFMCN ; WSYCGKRFTR ; SDELQRHKRT ; HTGEKKFACP ; ECPKRFMRSD ; 750: HLSKHIKTHQ ; NKKGGPGVAL ; SVGTLPLDSG ; AGSEGTATPS ; ALITTNMVAM ; 784: EAICPEGIAR ; LANSGINVMQ ; VTELQSINIS ; GNGF
Sequence Length	784
String	O89090
Sub Unit	Interacts with ATF7IP, ATF7IP2, BAHD1, POGZ, HCFC1, AATF and PHC2. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the 2 proteins in DNA binding. Interacts with HLTF; the interaction may be required for basal transcriptional activity of HLTF. Interacts (deacetylated form) with EP300; the interaction enhances gene expression. Interacts with HDAC1 and JUN. Interacts with ELF1; the interaction is inhibited by glycosylation of SP1. Interaction with NFYA; the interaction is inhibited by glycosylation of SP1. Interacts with SMARCA4/BRG1 (By similarity). Interacts with ATF7IP and TBP(By similarity).

Uniprot	O89090
Gene Name	Sp1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:20683
Unigene	Mm.4618

Reference	1. "Sp family transcription factors regulate expression of rat D2 dopamine receptor gene." Yajima S., Lee S.H., Minowa T., Mouradian M.M. DNA Cell Biol.17:471-479(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) tissue: Neuroblastoma. 2. "An alteatively spliced form of the transcription factor Sp1 containing only a single glutamine-rich transactivation domain." Persengiev S.P., Saffer J.D., Kilpatrick D.L. Proc. Natl. Acad. Sci. U.S.A.92:9107-9111(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) 3. "Isolation of cDNA encoding transcription factor sp1 containing two glutamine-rich transactivation domain." Park E.J., Kim J.H., Kim C.G., Park S.D., Hong S.S. Submitted (1997-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) tissue: Thymus. 4. "Difference in the genomic organizations of the related transcription factors Sp1 and Krox-20; possible evolutionary significance." Chestier A., Chaay P. DNA Seq.2:325-327(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 684-784 5. "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS] tissue: Liver. 6. "Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1." Xiao J., Zhou Y., Lai H., Lei S., Chi L.H., Mo X. J. Biol. Chem.288:31930-31936(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13809926	E15093m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.