ELISA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Mfr.No.

E2883m

Alternative Names

Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 ; TGF-beta-activated kinase 1-binding protein 1 ; TAK1-binding protein 1 ; Map3k7ip1

Categories

Elisa

Function

May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.

Specificity

Natural and recombinant Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Detection Range

78-5000pg/ml

Entryname

TAB1_MOUSE

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

Method Type

Sandwich

Platform

PF00481

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.7%

Protein Name

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Recovery

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

Sensitivity

39.5pg/mL

Sequence

50:

MAAQRRSLLQ ; SEQQPSWTDD ; LPLCHLSGVG ; SASNRSYSAD ; GKGTESHPPE ;

100:

DNWLKFRSEN ; NCFLYGVFNG ; YDGNRVTNFV ; AQRLSAELLL ; GQLNTEHTEA ;

150:

DVRRVLLQAF ; DVVERSFLES ; IDDALAEKAS ; LQSQLPEGVP ; QHQLPPQYQK ;

200:

ILERLKALER ; EISGGAMAVV ; AVLLNSKLYV ; ANVGTNRALL ; CKSTVDGLQV ;

250:

TQLNMDHTTE ; NEDELFRLSQ ; LGLDAGKIKQ ; MGVICGQEST ; RRIGDYKVKY ;

300:

GYTDIDLLSA ; AKSKPIIAEP ; EIHGAQPLDG ; VTGFLVLMSE ; GLYKALEAAH ;

350:

GPGQANQEIA ; AMIDTEFAKQ ; TSLDAVAQAV ; VDRVKRIHSD ; TFASGGERAK ;

400:

FCPRHEDMTL ; LVRNFGYPLG ; EMSQPTPTPA ; PGGRVYPVSV ; PYSSAQSTSK ;

450:

TSVTLSLVMP ; SQGQMVNGSH ; SASTLDEATP ; TLTNQSPTLT ; LQSTNTHTQS ;

500:

SSSSSDGGLF ; RSRPAHSLPP ; GEDGRVEPYV ; DFAEFYRLWS ; VDHGEQSVMT ;

502:

Sequence Length

502

String

Q8CF89

Sub Unit

Interacts with XIAP and BIRC7. Interacts with TRAF6 and MAP3K7; during IL-1 signaling. Identified in the TRIKA2 complex composed of MAP3K7, TAB1 and TAB2.

Uniprot	Q8CF89
Gene Name	Tab1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:66513
Unigene	Mm.288245

Reference	1. "Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis." Komatsu Y., Shibuya H., Takeda N., Ninomiya-Tsuji J., Yasui T., Miyado K., Sekimoto T., Ueno N., Matsumoto K., Yamada G. Mech. Dev.119:239-249(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: FVB/N. tissue: Eye. tissue: Kidney. tissue: Mammary tumor.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810523	E2883m	96T	$776		Add to Cart

ELISA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

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