ELISA Kit for Mouse Testin

Mfr.No.	E15045m
Alternative Names	TES1/TES2
Categories	Elisa
Function	Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor.
Specificity	Natural and recombinant Mouse Testin
Subcellular Location	Cytoplasm Cell junction focal adhesion Detected along actin stress fibers (By similarity). Detected at the subacrosomal layer in round spermatids.
Entryname	TES_MOUSE
Method Type	Sandwich
Platform	PF00412
Protein Name	Testin
Sequence	50: MSATHPTRLG ; TRTKESNACA ; SQGLVRKPPW ; ANEGEGFELH ; FWRKICRNCN ; 100: VVKKSMTVLL ; SNEEDRKVGR ; LFEDTKYTTL ; IAKLKSDGIP ; MYKRNVMILT ; 150: NPVAAKKNVS ; INTVTYEWAP ; PVQNQALARQ ; YMQMLPKEKQ ; PVAGSEGAQY ; 200: RKKQLAKQLP ; AHDQDPSKCH ; ELSPKEVKEM ; EQFVKKYKSE ; ALGVGDVKFP ; 250: SEMNAQGDKV ; HNCGNRHAPA ; AVASKDKSAE ; SKKTQYSCYC ; CKHTTNEGEP ; 300: AIYAERAGYD ; KLWHPACFIC ; STCGELLVDM ; IYFWKNGKLY ; CGRHYCDSEK ; 350: PRCAGCDELI ; FSNEYTQAEN ; QNWHLKHFCC ; FDCDHILAGK ; IYVMVTDKPV ; 400: CKPCYVKNHA ; VVCQGCHNAI ; DPEVQRVTYN ; NFSWHASTEC ; FLCSCCSKCL ; 423: IGQKFMPVEG ; MVFCSVECKR ; MMS
Sequence Length	423
String	P47226
Sub Unit	Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with talin, actin, alpha-actinin, GRIP1 and PXN. Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.

Reference	1. "Cloning and characterisation of two new cDNAs encoding murine triple LIM domains." Divecha N., Charleston B. Gene156:283-286(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS TES1 AND TES2) tissue: Testis. 2. "Knockout mice reveal a tumor suppressor function for Testin." Drusco A., Zanesi N., Roldo C., Trapasso F., Farber J.L., Fong L.Y., Croce C.M. Proc. Natl. Acad. Sci. U.S.A.102:10947-10951(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE 3. "Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A." Boeda B., Knowles P.P., Briggs D.C., Murray-Rust J., Soriano E., Garvalov B.K., McDonald N.Q., Way M. J. Biol. Chem.286:11543-11554(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13811037	E15045m	96T	$776		Add to Cart