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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Tenascin-R

SKU : BHE13811326

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1328m
Alternative Names	Janusin ; Neural recognition molecule J1-160/180 ; Restrictin
Categories	Elisa
Function	Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. Theses interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediates inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance.
Specificity	Natural and recombinant Mouse Tenascin-R
Subcellular Location	Secreted extracellular space extracellular matrix
Detection Range	1.56-100ng/mL
Entryname	TENR_MOUSE
Method Type	Sandwich
Platform	PF07974
Protein Name	Tenascin-R
Sensitivity	0.792ng/mL
Sequence	50: MGIDGETVVL ; KNMLIGVNLI ; LLGSMLKPSE ; CRLEVTTERA ; QRQTVEEEGG ; 100: ASSYNTSSKE ; QPMVFNHVYN ; INVPLESLCS ; SGLEASAEQD ; MSAEDDTLAE ; 150: YIGQTSDHES ; QVTFTHKINL ; PKKACPCASS ; SQVLQELLSR ; IEMLEREVSL ; 200: LRDQCNTNCC ; QESAATGQLD ; YVPHCSGHGN ; FSFESCGCIC ; NEGWFGKNCS ; 250: EPYCPLGCSS ; RGVCVDGQCI ; CDSEYSGDDC ; SELRCPTDCS ; SRGLCVDGEC ; 300: VCEEPYTGED ; CRELRCPGDC ; SGKGQCANGT ; CLCQEGYAGE ; DCSQRRCLNA ; 350: CSGRGHCQEG ; LCICEEGYQG ; PDCSAVAPPE ; DLRVAGISDR ; SIELEWDGPM ; 400: AVTEYVISYQ ; PTALGGLQLQ ; QRVPGDWSGV ; TIMELEPGLT ; YNISVYAVIS ; 450: NILSLPITAK ; VATHLSTPQG ; LQFKTITETT ; VEVQWEPFSF ; SFDGWEISFI ; 500: PKNNEGGVIA ; QLPSDVTSFN ; QTGLKPGEEY ; IVNVVALKEQ ; ARSPPTSASV ; 550: STVIDGPTQI ; LVRDVSDTVA ; FVEWTPPRAK ; VDFILLKYGL ; VGGEGGKTTF ; 600: RLQPPLSQYS ; VQALRPGSRY ; EVSISAVRGT ; NESEASSTQF ; TTEIDAPKNL ; 650: RVGSRTATSL ; DLEWDNSEAE ; AQEYKVVYST ; LAGEQYHEVL ; VPKGIGPTTK ; 700: TTLTDLVPGT ; EYGVGISAVM ; NSKQSIPATM ; NARTELDSPR ; DLMVTASSET ; 750: SISLIWTKAS ; GPIDHYRITF ; TPSSGISSEV ; TVPRDRTSYT ; LTDLEPGAEY ; 800: IISITAERGR ; QQSLESTVDA ; FTGFRPISHL ; HFSHVTSSSV ; NITWSDPSPP ; 850: ADRLILNYSP ; RDKEEDMLEV ; LLDATKRHAV ; LMGLQPATEY ; IVNLVAVHGT ; 900: VTSEPIVGSI ; TTGIDPPKNI ; TISNVTKDSL ; TVSWSSPVAP ; FDYYRVSYRP ; 950: TQVGRLDSSV ; VPNTVTEFAI ; TRLYPATEYE ; ISLNSVRGRE ; ESERICTLVH ; 1000: TAMDSPMDLI ; ATNITPTEAL ; LQWKAPMGEV ; ENYVIVLTHF ; AIAGETILVD ; 1050: GVSEEFQLVD ; LLPSTHYTVT ; MYATSGPLMS ; GTIATNFSTL ; LDPPDNLTAS ; 1100: EVTRQSALIS ; WQPPRAAIEN ; YVLTYKSTDG ; SRKELIVDAE ; DTWIRLEGLS ; 1150: ENTDYTVLLQ ; AAQEATRSSL ; TSTVFTTGGR ; VFSHPQDCAQ ; HLMNGDTLSG ; 1200: VYTIFLNGEL ; SHKLQVYCDM ; TTDGGGWIVF ; QRRQNGQTDF ; FRKWADYRVG ; 1250: FGNLEDEFWL ; GLDNIHRITA ; QGRYELRVDM ; RDGQEAVFAY ; YDKFAVEDSR ; 1300: SLYKIRIGSY ; NGTAGDSLSY ; HQGRPFSTED ; RDNDVAVTNC ; AMSYKGAWWY ; 1350: KNCHRTNLNG ; KYGESRHSQG ; INWYHWKGHE ; FSIPFVEMKM ; RPYIHRLTAG ; 1358: RKRRALKF
Sequence Length	1358
String	Q8BYI9
Sub Unit	Interacts with BCAN and AGC1 in a calcium-dependent manner. Interacts with SCN2B, PTPRZ1, and CSPG3 (By similarity). Forms oligomers. Isoforms 1 and 2 form respectively trimeric (tribrachion) and dimeric kink-armed rodlike structures, which are linked by disulfide bridges. Interacts with CNTN1, TNC and FN1.

Uniprot	Q8BYI9
Gene Name	Tnr
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21960
Unigene	Mm.44701

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811326	E1328m	96T	$776		Add to Cart

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