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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Sterol regulatory element-binding protein 2

SKU : BHE13810711

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12196m
Alternative Names	Sterol regulatory element-binding transcription factor 2 ; Srebp2
Categories	Elisa
Function	Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Specificity	Natural and recombinant Mouse Sterol regulatory element-binding protein 2
Subcellular Location	Processed sterol regulatory element-binding protein 2 Nucleus
Detection Range	0.312-20ng/mL
Entryname	SRBP2_MOUSE
Method Type	Sandwich
Platform	PF00010
Protein Name	Sterol regulatory element-binding protein 2
Sensitivity	0.166ng/mL
Sequence	50: MDESSELGVL ; ETMETLTELG ; DELTLGDIDE ; MLQFVSNQVG ; EFPDLFSEQL ; 100: CSSFPGGGSN ; GGSGNNSSGR ; GNNGGATDPA ; VQRSFSQVPL ; STFSPSAASP ; 150: QAPALQVKVS ; PTPPRATPVL ; QPRPQPQPQP ; PAQLQQQTVM ; ITPTFSTAPQ ; 200: TRIIQQPLIY ; QNAATSFQVL ; QPQVQSLVTS ; PQVQPVTIQQ ; QVQTVQAQRV ; 250: LTQTANGTLQ ; TLAPATVQTV ; AAPQVQQVPV ; LVQPQIIKTD ; SLVLTTLKTD ; 300: GSPVMAAVQN ; PALTALTAPI ; QTAALQVPTL ; VGSNGTILTT ; MPVMMGQEKV ; 350: PIKQVPGGVK ; QLDPPKEGER ; RTTHNIIEKR ; YRSSINDKII ; ELKDLVMGTD ; 400: AKMHKSGVLR ; KAIDYIKYLQ ; QVNHKLRQEN ; MVLKLANQKN ; KLLKGIDLGS ; 450: LVDSDVDLKI ; DDFNQNVLLM ; SPPASDSGSQ ; AGFSPYSIDS ; EPGSPLLDDA ; 500: KVKDEPDSPP ; VALGMVDRSR ; ILLCVLTFLG ; LSFNPLTSLL ; QWGGAHNTDQ ; 550: HPYSGSGRSV ; LSLESGAGGW ; FDWMVPTLLL ; WLVNGVIVLS ; VFVKLLVHGE ; 600: PVIRPHSRPS ; VTFWRHRKQA ; DLDLAKGDFA ; AAAANLQTCL ; SVLGRALPTS ; 650: RLDLACSLSW ; NVIRYSLQKL ; RLVRWLLKKV ; FQRWRATPAT ; AAGFEDEAKS ; 700: SARDAALAYH ; RLHQLHITGK ; LPAGSACSDV ; HMALCAVNLA ; ECAEEKILPS ; 750: TLIEIHLTAA ; MGLKTRCGGK ; LGFLASYFLN ; RAQSLCGPEH ; STVPDSLRWL ; 800: CHPLGQKFFM ; ERSWSIKSAA ; KESLYCAQRS ; PADPIAQVHQ ; AFCKNLLERA ; 850: VESLVKPQAK ; KKAGDQEEES ; CEFSSALEYL ; KLLHSFVDSV ; GFVTSPFSSS ; 900: SVLRSALGPD ; VICRWWTSAV ; TMAISWLQGD ; DAAVRSRFTE ; VERVPKALEV ; 950: TESPLVKAVF ; YTCRAMHASL ; SGKADGQQNS ; FCHCERASGH ; LWSSLNVSGT ; 1000: TSDPSLNHVI ; QLFTCDLLLS ; LRTALWQKQA ; SASQLLGETY ; HASGTELAGF ; 1050: QRDLGSLRRL ; AHSFRPAYRK ; VFLHEATVRL ; MAGASPTRTH ; QLLEHSLRRR ; 1100: PTQNTKHGEV ; DTWPGQRERA ; TAILLACRHL ; PLSFLSSPGQ ; RAVLLAEAAR ; 1130: TLEKVGDRRS ; CSDCQQMIVK ; LGGGTAIAAS ;
Sequence Length	1130
String	Q3U1N2
Sub Unit	Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein (By similarity). Interacts with LMNA. Component of SCAP/SREBP complex composed of SREBF2, SCAP and RNF139; the complex hampers the interaction between SCAP and SEC24B, thereby reducing SREBF2 proteolytic processing. Interacts (via C-terminus domain) with RNF139.

Uniprot	Q3U1N2
Gene Name	Srebf2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:20788
Unigene	Mm.38016

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810711	E12196m	96T	$776		Add to Cart

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