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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Sigma non-opioid intracellular receptor 1

SKU : BHE13810115

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E5642m
Alternative Names	Sigma 1-type opioid receptor ; Sigma1-receptor ; Oprs1
Categories	Elisa
Function	Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
Specificity	Natural and recombinant Mouse Sigma non-opioid intracellular receptor 1
Subcellular Location	Nucleus inner membrane Nucleus outer membrane Endoplasmic reticulum membrane Lipid droplet Cell junction Cell membrane Cell projection growth cone Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum. Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand-binding.
Entryname	SGMR1_MOUSE
Platform	PF04622
Protein Name	Sigma non-opioid intracellular receptor 1
Sequence	50: MPWAAGRRWA ; WITLILTIIA ; VLIQAAWLWL ; GTQNFVFSRE ; EIAQLARQYA ; 100: GLDHELAFSR ; LIVELRRLHP ; GHVLPDEELQ ; WVFVNAGGWM ; GAMCILHASL ; 150: SEYVLLFGTA ; LGSHGHSGRY ; WAEISDTIIS ; GTFHQWKEGT ; TKSEVFYPGE ; 200: TVVHGPGEAT ; ALEWGPNTWM ; VEYGRGVIPS ; TLFFALADTF ; FSTQDYLTLF ; 223: YTLRAYARGL ; RLELTTYLFG ; QDS
Sequence Length	223
String	O55242
Sub Unit	Interacts with KCNA4 (By similarity). Forms a ternary complex with ANK2 and ITPR3. The complex is disrupted by agonists.

Uniprot	O55242
Gene Name	Sigmar1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:18391
Unigene	Mm.425181

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810115	E5642m	96T	$776		Add to Cart

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