ELISA Kit for Mouse Radiation-inducible immediate-early gene IEX-1

Mfr.No.	E12474m
Antigen	IER3
Alternative Names	Immediate early protein GLY96 ; Immediate early response 3 protein ; Gly96 ; Iex1
Categories	Elisa
Function	May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme.
Specificity	Natural and recombinant Mouse Radiation-inducible immediate-early gene IEX-1
Subcellular Location	Membrane Single-pass type II membrane protein
Entryname	IEX1_MOUSE
Protein Name	Radiation-inducible immediate-early gene IEX-1
Sequence	50: MCHSRNHLHT ; MTGLRAPSPA ; PSTGPELRRG ; SGPEIFTFDP ; LPERAVVSTA ; 100: RLNTSRGHRK ; RSRRVLYPRV ; VRRQLPTEEP ; NIAKRVLFLL ; FAIIFCQILM ; 150: AEEGVSQPLA ; PEDATSAVTP ; EPISAPITAP ; PVLEPLNLTS ; ESSDYALDLK ; 153: AFL
Sequence Length	153
String	P46694
Sub Unit	Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.

Reference	1. "Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein." Charles C.H., Yoon J.K., Simske J.S., Lau L.F. Oncogene8:797-801(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: BALB/c. 2. "Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis." Hamidi T., Algul H., Cano C.E., Sandi M.J., Molejon M.I., Riemann M., Calvo E.L., Lomberk G., Dagorn J.C., Weih F., Urrutia R., Schmid R.M., Iovanna J.L. J. Clin. Invest.122:2092-2103(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805571	E12474m	96T	$776		Add to Cart