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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Polymerase I and transcript release factor

SKU : BHE13809635

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15153m
Alternative Names	Cav-p60 ; Cavin-1
Categories	Elisa
Function	Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.
Specificity	Natural and recombinant Mouse Polymerase I and transcript release factor
Subcellular Location	Membrane caveola Cell membrane Microsome Endoplasmic reticulum Cytoplasm cytosol Mitochondrion Nucleus Found at the surface of the caveolae. Also found in the plasma membrane, microsomal and cytosolic fractions and at a low level in the mitochondrial and nuclear fractions (By similarity). Translocates to the cytoplasm from caveolae upon insulin stimulation (By similarity). CAV1 is necessary to recruit it to the cell membrane. Co-localizes with CAV1 in lipid rafts in adipocytes.
Detection Range	78-5000pg/ml
Entryname	PTRF_MOUSE
Method Type	Sandwich
Platform	PF15237
Protein Name	Polymerase I and transcript release factor
Sensitivity	39pg/mL
Sequence	50: MEDVTLHIVE ; RPYSGFPDAS ; SEGPEPTQGE ; ARATEEPSGT ; GSDELIKSDQ ; 100: VNGVLVLSLL ; DKIIGAVDQI ; QLTQAQLEER ; QAEMEGAVQS ; IQGELSKLGK ; 150: AHATTSNTVS ; KLLEKVRKVS ; VNVKTVRGSL ; ERQAGQIKKL ; EVNEAELLRR ; 200: RNFKVMIYQD ; EVKLPAKLSV ; SKSLKESEAL ; PEKEGDELGE ; GERPEDDTAA ; 250: IELSSDEAVE ; VEEVIEESRA ; ERIKRSGLRR ; VDDFKKAFSK ; EKMEKTKVRT ; 300: RENLEKTRLK ; TKENLEKTRH ; TLEKRMNKLG ; TRLVPVERRE ; KLKTSRDKLR ; 350: KSFTPDHVVY ; ARSKTAVYKV ; PPFTFHVKKI ; REGEVEVLKA ; TEMVEVGPED ; 392: DEVGAERGEA ; TDLLRGSSPD ; VHTLLEITEE ; SDAVLVDKSD ; SD
Sequence Length	392
String	O54724
Sub Unit	Interacts with LIPE in the adipocyte cytoplasm (By similarity). Interacts with RNA polymerase I and TTF1. Binds the 3' end of pre-rRNA. Interacts with transcription factor ZNF148.

Uniprot	O54724
Gene Name	Ptrf
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:19285
Unigene	Mm.21864

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809635	E15153m	96T	$776		Add to Cart

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