Polycystic kidney disease 2 protein homolog ; Transient receptor potential cation channel subfamily P member 2 ; TRPP2
Categories
Elisa
Function
Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis.
Specificity
Natural and recombinant Mouse Polycystin-2
Subcellular Location
Membrane Multi-pass membrane protein Endoplasmic reticulum
Forms homooligomers. Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. Interacts with HAX1 (By similarity). Interacts with NEK8.