Phosphatidylinositol-glycan biosynthesis class Y protein ; PIG-Y ; Pigyl
Categories
Elisa
Function
Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins. May act by regulating the catalytic subunit PIGA.
Specificity
Natural and recombinant Mouse Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein
Entryname
PIGY_MOUSE
Protein Name
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Interacts with the GPI-GnT complex composed of PIGA, PIGC, PIGH, PIGP, PIGQ and DPM2. Interacts directly with PIGA. Does not interact with Ras proteins.