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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Oxidized low-density lipoprotein receptor 1

SKU : BHE13808224

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1859m
Alternative Names	Lectin-like oxidized LDL receptor 1 ; LOX-1 ; Lectin-type oxidized LDL receptor 1 ; Lox1
Categories	Elisa
Function	Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Specificity	Natural and recombinant Mouse Oxidized low-density lipoprotein receptor 1
Subcellular Location	Cell membrane Single-pass type II membrane protein Secreted A secreted form also exists.
Detection Range	0.78-50ng/mL
Entryname	OLR1_MOUSE
Method Type	Sandwich
Platform	PF00059
Protein Name	Oxidized low-density lipoprotein receptor 1
Sensitivity	0.39ng/mL
Sequence	50: MTFDDKMKPA ; NDEPDQKSCG ; KKPKGLHLLS ; SPWWFPAAMT ; LVILCLVLSV ; 100: TLIVQWTQLR ; QVSDLLKQYQ ; ANLTQQDRIL ; EGQMLAQQKA ; ENTSQESKKE ; 150: LKGKIDTLTQ ; KLNEKSKEQE ; ELLQKNQNLQ ; EALQRAANSS ; EESQRELKGK ; 200: IDTITRKLDE ; KSKEQEELLQ ; MIQNLQEALQ ; RAANSSEESQ ; RELKGKIDTL ; 250: TLKLNEKSKE ; QEELLQKNQN ; LQEALQRAAN ; FSGPCPQDWL ; WHKENCYLFH ; 300: GPFSWEKNRQ ; TCQSLGGQLL ; QINGADDLTF ; ILQAISHTTS ; PFWIGLHRKK ; 350: PGQPWLWENG ; TPLNFQFFKT ; RGVSLQLYSS ; GNCAYLQDGA ; VFAENCILIA ; 363: FSICQKKTNH ; LQI
Sequence Length	363
String	Q9EQ09
Sub Unit	Homodimer; disulfide-linked. May form a hexamer composed of 3 homodimers. Interacts with HSP70.

Uniprot	Q9EQ09
Gene Name	Olr1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:108078
Unigene	Mm.293626

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808224	E1859m	96T	$776		Add to Cart

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