Caspase recruitment domain-containing protein 4 ; Card4
Categories
Elisa
Function
Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens.
Specificity
Natural and recombinant Mouse Nucleotide-binding oligomerization domain-containing protein 1
Subcellular Location
Cytoplasm Basolateral cell membrane Recruited to the basolateral membrane compartment in polarized epithelial cells.