Binds to promoters containing the sequence element 5'-AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development.
Specificity
Natural and recombinant Mouse Nuclear receptor subfamily 5 group A member 2
"LRH-1: a nuclear hormone receptor active in the absence of exogenous ligands." Tugwood J.D., Issemann I., Green S. Submitted (1992-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 313-560;INTERACTION WITH NR0B2 AND GRIP1
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 318-560 IN COMPLEX WITH NR0B2
Reviews of ELISA Kit for Mouse Nuclear receptor subfamily 5 group A member 2