Calcineurin/NFAT-activating ITAM-containing protein ; NFAT-activating protein with ITAM motif 1 ; Cnaip
Categories
Elisa
Function
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters (By similarity). May be involved in the regulation of B-cell, but not T-cell, development.
Specificity
Natural and recombinant Mouse NFAT activation molecule 1
Subcellular Location
Cell membrane Single-pass type I membrane protein Partially recruited to lipid rafts upon BCR stimulation.