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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Mothers against decapentaplegic homolog 1

SKU : BHE13809810

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0647m
Alternative Names	Dwarfin-A ; Dwf-A ; Mothers-against-DPP-related 1 ; Mad-related protein 1 ; SMAD family member 1 ; SMAD 1 ; Madh1 ; Madr1
Categories	Elisa
Function	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Specificity	Natural and recombinant Mouse Mothers against decapentaplegic homolog 1
Subcellular Location	Cytoplasm Nucleus In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane.
Detection Range	62.5-4000pg/mL
Entryname	SMAD1_MOUSE
Method Type	Sandwich
Platform	PF03165
Protein Name	Mothers against decapentaplegic homolog 1
Sensitivity	31.34pg/mL
Sequence	50: MNVTSLFSFT ; SPAVKRLLGW ; KQGDEEEKWA ; EKAVDALVKK ; LKKKKGAMEE ; 100: LEKALSCPGQ ; PSNCVTIPRS ; LDGRLQVSHR ; KGLPHVIYCR ; VWRWPDLQSH ; 150: HELKPLECCE ; FPFGSKQKEV ; CINPYHYKRV ; ESPVLPPVLV ; PRHSEYNPQH ; 200: SLLAQFRNLG ; QNEPHMPLNA ; TFPDSFQQPN ; SHPFPHSPNS ; SYPNSPGGSS ; 250: STYPHSPTSS ; DPGSPFQMPA ; DTPPPAYLPP ; EDPMAQDGSQ ; PMDTNMMAPP ; 300: LPAEISRGDV ; QAVAYEEPKH ; WCSIVYYELN ; NRVGEAFHAS ; STSVLVDGFT ; 350: DPSNNKNRFC ; LGLLSNVNRN ; STIENTRRHI ; GKGVHLYYVG ; GEVYAECLSD ; 400: SSIFVQSRNC ; NYHHGFHPTT ; VCKIPSGCSL ; KIFNNQEFAQ ; LLAQSVNHGF ; 450: ETVYELTKMC ; TIRMSFVKGW ; GAEYHRQDVT ; STPCWIEIHL ; HGPLQWLDKV ; 465: LTQMGSPHNP ; ISSVS
Sequence Length	465
String	P70340
Sub Unit	May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), p300, SMURF1, SMURF2 and HOXC8. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with SKOR1. Interacts (via MH2 domain) with LEMD3. Binding to LEMD3 results in at least a partial reduction of receptor-mediated phosphorylation (By similarity). Also interacts with HGS, NANOG and ZCCHC12. Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome.

Uniprot	P70340
Gene Name	Smad1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:17125
Unigene	Mm.223717

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809810	E0647m	96T	$776		Add to Cart

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