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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Mitogen-activated protein kinase 14

SKU : BHE13807028

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9114m
Alternative Names	CRK1 ; Mitogen-activated protein kinase p38 alpha ; MAP kinase p38 alpha ; Crk1 ; Csbp1 ; Csbp2
Categories	Elisa
Function	Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.
Specificity	Natural and recombinant Mouse Mitogen-activated protein kinase 14
Subcellular Location	Cytoplasm Nucleus
Detection Range	0.156-10ng/mL
Entryname	MK14_MOUSE
Method Type	Sandwich
Platform	PF00069
Protein Name	Mitogen-activated protein kinase 14
Sensitivity	0.078ng/mL
Sequence	50: MSQERPTFYR ; QELNKTIWEV ; PERYQNLSPV ; GSGAYGSVCA ; AFDTKTGHRV ; 100: AVKKLSRPFQ ; SIIHAKRTYR ; ELRLLKHMKH ; ENVIGLLDVF ; TPARSLEEFN ; 150: DVYLVTHLMG ; ADLNNIVKCQ ; KLTDDHVQFL ; IYQILRGLKY ; IHSADIIHRD ; 200: LKPSNLAVNE ; DCELKILDFG ; LARHTDDEMT ; GYVATRWYRA ; PEIMLNWMHY ; 250: NQTVDIWSVG ; CIMAELLTGR ; TLFPGTDHID ; QLKLILRLVG ; TPGAELLKKI ; 300: SSESARNYIQ ; SLAQMPKMNF ; ANVFIGANPL ; AVDLLEKMLV ; LDSDKRITAA ; 350: QALAHAYFAQ ; YHDPDDEPVA ; DPYDQSFESR ; DLLIDEWKSL ; TYDEVISFVP ; 360: PPLDQEEMES ;
Sequence Length	360
String	P47811
Sub Unit	Interacts with NP60 (By similarity). Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR. This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with SPAG9 and FAM48A.

Uniprot	P47811
Gene Name	Mapk14
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:26416
Unigene	Mm.311337

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SKU	Supplier No.	Size	Your price	Quantity
BHE13807028	E9114m	96T	$776		Add to Cart

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