ELISA Kit for Mouse Mitochondrial genome maintenance exonuclease 1

Mfr.No.	E15155m
Categories	Elisa
Function	Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair (By similarity). Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Specificity	Natural and recombinant Mouse Mitochondrial genome maintenance exonuclease 1
Subcellular Location	Mitochondrion
Entryname	MGME1_MOUSE
Method Type	Sandwich
Protein Name	Mitochondrial genome maintenance exonuclease 1
Sequence	50: MKLPLTFCRL ; LSRLNRFSVK ; ASPPVSFSTF ; SYLCSQKKKN ; SYEAVDQAKY ; 100: SRLVRSVLSR ; GPAQTPESLF ; KEDDVLYGPV ; SKHKAAEPEP ; QARVPQHCFP ; 150: IFNEERTGKP ; HTDASSSPLK ; IPLQRNSIPS ; VTRILQQTMP ; PEQSFFLERW ; 200: KERMVLELGE ; DGFAEYTSNV ; FLQGKQFHKA ; LESILSPQEN ; LTGGEEHPQC ; 250: GYIESIQHIL ; TEISGVQALE ; SAVQHEALKY ; VGLLDCVAEY ; RGKLCVIDWK ; 300: TSEKPKPLIR ; NTYDNPLQVV ; AYMGAVNHDA ; HYSFQVQCGL ; IVVAYKDGSP ; 338: AHPHFMDEEL ; CSKYWAKWLL ; RLEEYTEKQK ; NLSAPEPA
Sequence Length	338

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806445	E15155m	96T	$776		Add to Cart