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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Meiotic recombination protein REC8 homolog

SKU : BHE13809376

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4955m
Alternative Names	Cohesin Rec8p ; Mei8 ; Rec8L1
Categories	Elisa
Function	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
Specificity	Natural and recombinant Mouse Meiotic recombination protein REC8 homolog
Subcellular Location	Nucleus Chromosome Chromosome centromere In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II.
Detection Range	0.78-50ng/mL
Entryname	REC8_MOUSE
Method Type	Sandwich
Platform	PF04824
Protein Name	Meiotic recombination protein REC8 homolog
Sensitivity	0.446ng/mL
Sequence	50: MFYYPNVLQR ; HTGCFATIWL ; AATRGSRLVK ; REYLNVNVVK ; TCEEILNYVL ; 100: VRVQPPVAGL ; PRPRFSLYLS ; AQLQIGVIRV ; YFQQCQYLVE ; DIQHILEHLH ; 150: RAQLRIRIDM ; EEADLPSLLL ; PNCLAMMETL ; EDAPEPFFGK ; MSVDPRLPSP ; 200: FDIPQIRHLL ; EAATPEKTRK ; ETLPEATPDP ; RKPDRTLATV ; QSPEVITLQE ; 250: AEPIRMLQIE ; GEQDLPEISR ; GDLELLIAEK ; DDAILLEERQ ; RGRLLRQRRA ; 300: SLPLDESREE ; PRALEGAGLV ; SALSPPAPAQ ; VEGIQEALPG ; QVFPPEVQKM ; 350: TGWEPGALLT ; EVTPPQELRL ; PAPPSTEKRL ; PSLQRPLPRR ; HRRRQLLFWD ; 400: KETQISREKF ; EEQLQTGAHC ; WEYPVAQPPK ; RMLTSPAELF ; RTPTLSGWLP ; 450: PELLGLWTHC ; AQVPQRMLRQ ; RPQLETEETV ; EEERAADEEE ; RRKTEALSEI ; 500: EVLREAQEPS ; GPLMLSSELS ; LEAAEDEKSR ; TSLIPPEWWA ; WSEEGQPEPP ; 550: ALPMLPELPE ; VPMEMPPRPE ; LSSEAVLRAV ; ALKLQANKEL ; DFSSLVPPLS ; 591: PRKLASRVFY ; LLLVLSTQKI ; LLVEQQKPYG ; PLLIRPGPKF ; P
Sequence Length	591
String	Q8C5S7
Sub Unit	Interacts (phosphorylated and unphosphorylated form) with SMC3. Interacts with SYCP3. Interacts (phosphorylated and unphosphorylated form) with SMC1B. Does not interact with SMC1A. Interacts with RAD51.

Uniprot	Q8C5S7
Gene Name	Rec8
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:56739
Unigene	Mm.23149

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809376	E4955m	96T	$776		Add to Cart

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