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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Macrophage migration inhibitory factor

SKU : BHE13806958

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0698m
Alternative Names	Delayed early response protein 6 ; DER6 ; Glycosylation-inhibiting factor ; GIF ; L-dopachrome isomerase ; L-dopachrome tautomerase ; 5.3.3.12 ; Phenylpyruvate tautomerase
Categories	Elisa
Function	Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Specificity	Natural and recombinant Mouse Macrophage migration inhibitory factor
Subcellular Location	Secreted Cytoplasm Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
Detection Range	62.5-4000pg/mL
Entryname	MIF_MOUSE
Method Type	Sandwich
Platform	PF01187
Protein Name	Macrophage migration inhibitory factor
Sensitivity	31.35pg/mL
Sequence	50: MPMFIVNTNV ; PRASVPEGFL ; SELTQQLAQA ; TGKPAQYIAV ; HVVPDQLMTF ; 100: SGTNDPCALC ; SLHSIGKIGG ; AQNRNYSKLL ; CGLLSDRLHI ; SPDRVYINYY ; 115: DMNAANVGWN ; GSTFA
Sequence Length	115
String	P34884
Sub Unit	Homotrimer. Interacts with BNIPL (By similarity). Interacts with the CD74 extracellular domain. Interacts with COPS5 and with the CXCR2 extracellular domain.

Uniprot	P34884
Gene Name	Mif
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:17319
Unigene	Mm.2326

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806958	E0698m	96T	$776		Add to Cart

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