May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95.
Specificity
Natural and recombinant Mouse Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma
Subcellular Location
Nucleus inner membrane Single-pass type II membrane protein Chromosome Tightly associated with the nuclear lamina.