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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Kelch-like protein 17

SKU : BHE13806736

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1567m
Alternative Names	Actinfilin
Categories	Elisa
Function	Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function.
Specificity	Natural and recombinant Mouse Kelch-like protein 17
Subcellular Location	Cell junction synapse postsynaptic cell membrane postsynaptic density Cell junction synapse Postsynaptic density.
Detection Range	62.5-4000pg/mL
Entryname	KLH17_MOUSE
Method Type	Sandwich
Platform	PF07707
Protein Name	Kelch-like protein 17
Sensitivity	31.42pg/mL
Sequence	50: MQPRGERPAG ; RTQSPEHSSP ; GPGPEAPPPP ; QPPAPEAERA ; RPRQARPAAP ; 100: MEGAMQLLSR ; EGHSVAHNSK ; RHYHDAFVAM ; SRMRQRGLLC ; DIVLHVAAKE ; 150: IRAHKVVLAS ; CSPYFHAMFT ; NEMSESRQTH ; VTLHDIDPQA ; LDQLVQFAYT ; 200: AEIVVGEGNV ; QTLLPAASLL ; QLNGVRDACC ; KFLLSQLDPS ; NCLGIRGFAD ; 250: THSCSDLLKA ; AHRYVLQHFV ; DVAKTEEFML ; LPLKQVLELV ; SSDSLNVPSE ; 300: EDVYRAVLSW ; VKHDVDTRRQ ; HVPRLMKCVR ; LPLLSRDFLL ; GHVDAESLVR ; 350: HHPDCKDLLI ; EALKFHLLPE ; QRGVLGTSRT ; RPRRCEGAGP ; VLFAVGGGSL ; 400: FAIHGDCEAY ; DTRTDRWHVV ; ASMSTRRARV ; GVAAVGNRLY ; AVGGYDGTSD ; 450: LATVESYDPV ; TNTWQPEVSM ; GTRRSCLGVA ; ALHGLLYAAG ; GYDGASCLNS ; 500: AERYDPLTGT ; WTSIAAMSTR ; RRYVRVATLD ; GNLYAVGGYD ; SSSHLATVEK ; 550: YEPQVNSWTP ; VASMLSRRSS ; AGVAVLEGAL ; YVAGGNDGTS ; CLNSVERYST ; 600: KAGAWESVAP ; MNIRRSTHDL ; VAMDGWLYAV ; GGNDGSSSLN ; SIEKYNPRTN ; 640: KWVAASCMFT ; RRSSVGVAVL ; ELLNFPPPSS ; PTLSVSSTSL ;
Sequence Length	640
String	Q6TDP3
Sub Unit	Interacts with F-actin; the interaction disruptes the F-actin structures and leads to marked changes of neuronal morphology. Component of a complex, composed of PDZK1, SYNGAP1, KLHL17 and NMDA receptors. Interacts directly with PDZK1 (via PDZ1 domain); the interaction is important for integrity of actin cytoskeleton structures in neurons. Interacts with DLG4 and SYNGAP1. Interacts (via kelch repeats) with GRIK2 (via C-terminus); the interaction targets GRIK2 for degradation via ubiquitin-proteasome pathway. Interacts with GRIK1. Interacts with (via BTB domain) CUL3; the inteaction regulates surface GRIK2 expression.

Uniprot	Q6TDP3
Gene Name	Klhl17
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:231003
Unigene	Mm.423038

Reference	1. Huang C.Q., Wu S.L., Shan Y.X. Submitted (2003-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C57BL/6J.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806736	E1567m	96T	$776		Add to Cart

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