ELISA Kit for Mouse Interleukin-3 receptor subunit alpha

Mfr.No.	E9249m
Alternative Names	Interleukin-3 receptor class II alpha chain ; CD123 ; Sut-1
Categories	Elisa
Function	In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors.
Specificity	Natural and recombinant Mouse Interleukin-3 receptor subunit alpha
Subcellular Location	Isoform 2 Endomembrane system Single-pass type I membrane protein Mostly distributed inside the cells, except in the nuclei and is not transported to the cell surface.
Detection Range	31.2-2000pg/mL
Entryname	IL3RA_MOUSE
Method Type	Sandwich
Platform	PF09240
Protein Name	Interleukin-3 receptor subunit alpha
Sensitivity	15.72pg/mL
Sequence	50: MAANLWLILG ; LLASHSSDLA ; AVREAPPTAV ; TTPIQNLHID ; PAHYTLSWDP ; 100: APGADITTGA ; FCRKGRDIFV ; WADPGLARCS ; FQSLSLCHVT ; NFTVFLGKDR ; 150: AVAGSIQFPP ; DDDGDHEAAA ; QDLRCWVHEG ; QLSCQWERGP ; KATGDVHYRM ; 200: FWRDVRLGPA ; HNRECPHYHS ; LDVNTAGPAP ; HGGHEGCTLD ; LDTVLGSTPN ; 250: SPDLVPQVTI ; TVNGSGRAGP ; VPCMDNTVDL ; QRAEVLAPPT ; LTVECNGSEA ; 300: HARWVARNRF ; HHGLLGYTLQ ; VNQSSRSEPQ ; EYNVSIPHFW ; VPNAGAISFR ; 350: VKSRSEVYPR ; KLSSWSEAWG ; LVCPPEVMPV ; KTALVTSVAT ; VLGAGLVAAG ; 396: LLLWWRKSLL ; YRLCPPIPRL ; RLPLAGEMVV ; WEPALEDCEV ; TPVTDA
Sequence Length	396
String	P26952
Sub Unit	Heterodimer of an alpha and a beta subunit.

Reference	1. "Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3)." Hara T., Miyajima A. EMBO J.11:1875-1884(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) strain: B6.S. 2. "Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene." Ichihara M., Hara T., Takagi M., Cho L.C., Gorman D.M., Miyajima A. EMBO J.14:939-950(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);SUBCELLULAR LOCATION strain: A/J. strain: C57BL/6. 3. "A new isoform of IL-3 receptor alpha with novel differentiation activity and high affinity binding mode." Chen J., Olsen J., Ford S., Mirza S., Walker A., Murphy J.M., Young I.G. J. Biol. Chem.284:5763-5773(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805916	E9249m	96T	$776		Add to Cart