JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Interleukin-21

SKU : BHE13805219

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E1688m
Categories	Elisa
Function	Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Specificity	Natural and recombinant Mouse Interleukin-21
Subcellular Location	Secreted
Detection Range	15.6-1000pg/mL
Entryname	IL21_MOUSE
Method Type	Sandwich
Platform	PF02372
Protein Name	Interleukin-21
Sensitivity	7.9pg/mL
Sequence	50: MERTLVCLVV ; IFLGTVAHKS ; SPQGPDRLLI ; RLRHLIDIVE ; QLKIYENDLD ; 100: PELLSAPQDV ; KGHCEHAAFA ; CFQKAKLKPS ; NPGNNKTFII ; DLVAQLRRRL ; 146: PARRGGKKQK ; HIAKCPSCDS ; YEKRTPKEFL ; ERLKWLLQKM ; IHQHLS
Sequence Length	146
String	Q9ES17

Uniprot	Q9ES17
Gene Name	Il21
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:60505
Unigene	Mm.157689

Reference	1. "Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function." Parrish-Novak J., Dillon S.R., Nelson A., Hammond A., Sprecher C., Gross J.A., Johnston J., Madden K., Xu W., West J., Schrader S., Burkhead S., Heipel M., Brandt C., Kuijper J.L., Kramer J., Conklin D., Presnell S.R., Berry J., Shiota F., Bort S., Hambly K., Mudri S., Clegg C., Moore M., Grant F.J., Lofton-Day C., Gilbert T., Raymond F., Ching A., Yao L., Smith D., Webster P., Whitmore T., Maurer M., Kaushansky K., Holly R.D., Foster D.more... Nature408:57-63(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: BALB/c. 2. "Mouse interleukin 21 can improve the anti-tumor effect of LAK cells." Guobing C., Jun D., Junsong C., Fenshu Z. Submitted (2003-10) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: BALB/c. 3. "IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity." Kasaian M.T., Whitters M.J., Carter L.L., Lowe L.D., Jussif J.M., Deng B., Johnson K.A., Witek J.S., Senices M., Konz R.F., Wurster A.L., Donaldson D.D., Collins M., Young D.A., Grusby M.J. Immunity16:559-569(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION 4. "Interleukin-21 inhibits dendritic cell activation and maturation." Brandt K., Bulfone-Paus S., Foster D.C., Rueckert R. Blood102:4090-4098(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION 5. "IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells." Pene J., Gauchat J.-F., Lecart S., Drouet E., Guglielmi P., Boulay V., Delwail A., Foster D., Lecron J.C., Yssel H. J. Immunol.172:5154-5157(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13805219	E1688m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.