JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Interleukin-17C

SKU : BHE13806318

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E8758m
Alternative Names	Cytokine CX2
Categories	Elisa
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis.
Specificity	Natural and recombinant Mouse Interleukin-17C
Subcellular Location	Secreted
Entryname	IL17C_MOUSE
Platform	PF06083
Protein Name	Interleukin-17C
Sequence	50: MSLLLLGWLP ; TGMTHQDPPS ; WGKPRSHRTL ; RCYSAEELSH ; GQAPPHLLTR ; 100: SARWEQALPV ; ALVASLEATG ; HRRQHEGPLA ; GTQCPVLRPE ; EVLEADTHER ; 150: SISPWRYRID ; TDENRYPQKL ; AVAECLCRGC ; INAKTGRETA ; ALNSVQLLQS ; 194: LLVLRRQPCS ; RDGTADPTPG ; SFAFHTEFIR ; VPVGCTCVLP ; RSTQ
Sequence Length	194
Sub Unit	Binds to a heterodimer formed by IL17RA and IL17RE.

Uniprot	Q8K4C5
Gene Name	Il17c
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:234836
Unigene	Mm.222808

Reference	1. "New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25." Hurst S.D., Muchamuel T., Gorman D.M., Gilbert J.M., Clifford T., Kwan S., Menon S., Seymour B., Jackson C., Kung T.T., Brieland J.K., Zurawski S.M., Chapman R.W., Zurawski G., Coffman R.L. J. Immunol.169:443-453(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-194 4. "Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E." Chang S.H., Reynolds J.M., Pappu B.P., Chen G., Martinez G.J., Dong C. Immunity35:611-621(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH IL17RA AND IL17RE;DISRUPTION PHENOTYPE 5. "IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens." Song X., Zhu S., Shi P., Liu Y., Shi Y., Levin S.D., Qian Y. Nat. Immunol.12:1151-1158(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH IL17RA AND IL17RE;INDUCTION 6. "IL-17C regulates the innate immune function of epithelial cells in an autocrine manner." Ramirez-Carrozzi V., Sambandam A., Luis E., Lin Z., Jeet S., Lesch J., Hackney J., Kim J., Zhou M., Lai J., Modrusan Z., Sai T., Lee W., Xu M., Caplazi P., Diehl L., de Voss J., Balazs M., Gonzalez L. Jr., Singh H., Ouyang W., Pappu R.more... Nat. Immunol.12:1159-1166(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13806318	E8758m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.