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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Interleukin-1 receptor type 1

SKU : BHE13804939

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0065m
Alternative Names	CD121 antigen-like family member A ; Interleukin-1 receptor alpha ; IL-1R-alpha ; Interleukin-1 receptor type I ; p80 ; CD121a ; Il-1r1 ; Il1ra
Categories	Elisa
Function	Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
Specificity	Natural and recombinant Mouse Interleukin-1 receptor type 1
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	IL1R1_MOUSE
Method Type	Sandwich
Platform	PF07679
Protein Name	Interleukin-1 receptor type 1
Sensitivity	40.1pg/mL
Sequence	50: MENMKVLLGL ; ICLMVPLLSL ; EIDVCTEYPN ; QIVLFLSVNE ; IDIRKCPLTP ; 100: NKMHGDTIIW ; YKNDSKTPIS ; ADRDSRIHQQ ; NEHLWFVPAK ; VEDSGYYYCI ; 150: VRNSTYCLKT ; KVTVTVLEND ; PGLCYSTQAT ; FPQRLHIAGD ; GSLVCPYVSY ; 200: FKDENNELPE ; VQWYKNCKPL ; LLDNVSFFGV ; KDKLLVRNVA ; EEHRGDYICR ; 250: MSYTFRGKQY ; PVTRVIQFIT ; IDENKRDRPV ; ILSPRNETIE ; ADPGSMIQLI ; 300: CNVTGQFSDL ; VYWKWNGSEI ; EWNDPFLAED ; YQFVEHPSTK ; RKYTLITTLN ; 350: ISEVKSQFYR ; YPFICVVKNT ; NIFESAHVQL ; IYPVPDFKNY ; LIGGFIILTA ; 400: TIVCCVCIYK ; VFKVDIVLWY ; RDSCSGFLPS ; KASDGKTYDA ; YILYPKTLGE ; 450: GSFSDLDTFV ; FKLLPEVLEG ; QFGYKLFIYG ; RDDYVGEDTI ; EVTNENVKKS ; 500: RRLIIILVRD ; MGGFSWLGQS ; SEEQIAIYNA ; LIQEGIKIVL ; LELEKIQDYE ; 550: KMPDSIQFIK ; QKHGVICWSG ; DFQERPQSAK ; TRFWKNLRYQ ; MPAQRRSPLS ; 576: KHRLLTLDPV ; RDTKEKLPAA ; THLPLG
Sequence Length	576
String	P13504
Sub Unit	Binds IL1RAP.

Uniprot	P13504
Gene Name	Il1r1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:16177
Unigene	Mm.896

Reference	1. "cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily." Sims J.E., March C.J., Cosman D., Widmer M.B., McDonald H.R., McMahan C.J., Grubin C.E., Wignall J.M., Jackson J.L., Call S.M., Friend D., Alpert A.R., Gillis S., Urdal D.L., Dower S.K. Science241:585-589(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 20-45 2. "Phorbol ester induces phosphorylation of the 80 kilodalton murine interleukin 1 receptor at a single threonine residue." Bird T.A., Woodward A., Jackson J.L., Dower S.K., Sims J.E. Biochem. Biophys. Res. Commun.177:61-67(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-556 3. "Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex." Greenfeder S.A., Nunes P., Kwee L., Labow M., Chizzonite R.A., Ju G. J. Biol. Chem.270:13757-13765(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL1RAP 4. "Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor." Burns K., Clatworthy J., Martin L., Martinon F., Plumpton C., Maschera B., Lewis A., Ray K., Tschopp J., Volpe F. Nat. Cell Biol.2:346-351(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TOLLIP; MYD88 AND IRAK1 5. "Modelling of fish interleukin-1 and its receptor." Scapigliati G., Costantini S., Colonna G., Facchiano A., Buonocore F., Bossu P., Cunningham C., Holland J.W., Secombes C.J. Dev. Comp. Immunol.28:429-441(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 25-334

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