ELISA Kit for Mouse Interleukin-1 alpha

Mfr.No.	E0071m
Categories	Elisa
Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Specificity	Natural and recombinant Mouse Interleukin-1 alpha
Subcellular Location	Secreted The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Detection Range	15.6-1000pg/mL
Entryname	IL1A_MOUSE
Method Type	Sandwich
Platform	PF00340
Protein Name	Interleukin-1 alpha
Sensitivity	7.9pg/mL
Sequence	50: MAKVPDLFED ; LKNCYSENED ; YSSAIDHLSL ; NQKSFYDASY ; GSLHETCTDQ ; 100: FVSLRTSETS ; KMSNFTFKES ; RVTVSATSSN ; GKILKKRRLS ; FSETFTEDDL ; 150: QSITHDLEET ; IQPRSAPYTY ; QSDLRYKLMK ; LVRQKFVMND ; SLNQTIYQDV ; 200: DKHYLSTTWL ; NDLQQEVKFD ; MYAYSSGGDD ; SKYPVTLKIS ; DSQLFVSAQG ; 250: EDQPVLLKEL ; PETPKLITGS ; ETDLIFFWKS ; INSKNYFTSA ; AYPELFIATK ; 270: EQSRVHLARG ; LPSMTDFQIS ;
Sequence Length	270
String	P01582
Sub Unit	Monomer.

Reference	1. "Cloning and expression of murine interleukin-1 cDNA in Escherichia coli." Lomedico P.T., Gubler U., Hellmann C.P., Dukovich M., Giri J.G., Pan Y.-C.E., Collier K., Semionow R., Chua A.O., Mizel S.B. Nature312:458-462(1984) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Complete nucleotide sequence of the murine interleukin-1 alpha gene." Kastelic T., Wanner A., Mackenzie A., Cheneval D. Submitted (1997-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] strain: BALB/c. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: FVB/N. tissue: Mammary gland. 4. "The precursor of interleukin-1 alpha is phosphorylated at residue serine 90." Beuscher H.U., Nickells M.W., Colten H.R. J. Biol. Chem.263:4023-4028(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-90

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13804943	E0071m	96T	$776		Add to Cart