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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Integrin alpha-V

SKU : BHE13806246

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0271m
Alternative Names	Vitronectin receptor subunit alpha ; CD51
Categories	Elisa
Function	The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. Mice expressing a null mutation of the alpha-V subunit gene survive until late in embryonic development and occasionally even to birth. They demonstrate cleft palate, and defective development of CNS and gastrointestinal blood vessels.
Specificity	Natural and recombinant Mouse Integrin alpha-V
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/ml
Entryname	ITAV_MOUSE
Method Type	Sandwich
Platform	PF01839
Protein Name	Integrin alpha-V
Sensitivity	39pg/mL
Sequence	50: MAAPGRLLLR ; PRPGGLLLLL ; PGLLLPLADA ; FNLDVESPAE ; YAGPEGSYFG ; 100: FAVDFFEPST ; SSRMFLLVGA ; PKANTTQPGI ; VEGGQVLKCE ; CSSSRRCQPI ; 150: EFDSTGNRDY ; AKDDPLEFKS ; HQWFGASVRS ; KQDKILACAP ; LYHWRTEMKQ ; 200: EREPVGTCFL ; QDGTKTVEYA ; PCRSKNIDAD ; GQGFCQGGFS ; IDFTKADRVL ; 250: LGGPGSFYWQ ; GQLISDQVAE ; IISKYDPNVY ; SIKYNNQLAT ; RTAQAIFDDS ; 300: YLGYSVAVGD ; FNGDGIEDFV ; SGVPRAARTL ; GMVYIYDGKN ; MSSLHNFTGE ; 350: QMAAYFGFSV ; AATDINGDDY ; ADVFIGAPLF ; MDRGSDGKLQ ; EVGQVSVSLQ ; 400: RAVGDFQTTK ; LNGFEVFARF ; GSAIAPLGDL ; DQDGFNDIAI ; AAPYGGEDKK ; 450: GLVYIFNGRS ; TGLNSVPSQI ; LEGQWAAQSM ; PPSFGYSMKG ; ATDVDRNGYP ; 500: DLVVGAFGVD ; RAVLYRARPV ; VTVNAGLEVY ; PSILNQDNKI ; CPLPGTALKV ; 550: SCFNVRFCLK ; ADGKGTLPRK ; LHFQVELLLD ; KLKQKGAIRR ; ALFLHNRSPV ; 600: HSKTMTVFRG ; GQMQCEELVA ; YLRDESEFRD ; KLTPITIFME ; YRLDQRTAAD ; 650: ATGLQPILNQ ; FTPANVSRQA ; HILLDCGEDN ; VCKPKLEVSV ; NSDQKKIYIG ; 700: DDNPLTLTVK ; AQNQGEGAYE ; AELIVSIPPQ ; ADFIGVVRNN ; EALARLSCAF ; 750: KTENQTRQVV ; CDLGNPMKAG ; TQLLAGLRFS ; VHQQSEMDTS ; VKFDLKIQSS ; 800: NSFDNVSPVV ; SYKVDLAVLA ; AVEIRGVSSP ; DHIFLPIPNW ; EYKENPETEE ; 850: DVGPIVQHIY ; ELRNNGPSSF ; SKAILNLQWP ; YKYNNNTLLY ; ILHYDIDGPM ; 900: NCTADTEINP ; LRIKTPEKND ; TAAAGQGERN ; HLITKRDLTL ; REGDVHTLGC ; 950: GIAKCLQITC ; QVGRLDRGKS ; AILYVKSLLW ; TETFMNKENQ ; NHSYSLKSSA ; 1000: SFNIIEFPYK ; NLPIEDLFNS ; TLVTTNITWG ; IQPAPMPVPV ; WVIILAVLAG ; 1044: LLLLAVLVFV ; MYRMGFFKRV ; RPPQEEQERE ; QLQPHENGEG ; NSET
Sequence Length	1044
String	P43406
Sub Unit	Interacts with RAB25 (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8.

Uniprot	P43406
Gene Name	Itgav
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:16410
Unigene	Mm.227

Reference	1. "Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development." Wada J., Kumar A., Liu Z., Ruoslahti E., Reichardt L., Marvaldi J., Kanwar Y.S. J. Cell Biol.132:1161-1176(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: CD-1. tissue: Kidney. 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation." Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I., Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E., Wollscheid B. Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615; ASN-869; ASN-939 AND ASN-941 tissue: Myoblast. 4. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins." Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D. Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615 AND ASN-869

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806246	E0271m	96T	$776		Add to Cart

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